103110-98-1Relevant articles and documents
Observation of a Stable Monomeric N-Methylene Aromatic Amine
Verardo, Giancarlo,Cauci, Sabina,Giumanini, Angelo G.
, p. 1787 - 1788 (1985)
The first free N-methyleneaniline stable under ordinary conditions was authenticated by spectroscopic and analytical data and some of its reactions were observed; a room temperature equilibrium between another free N-methylene aromatic amine and its oligomeric species is reported.
N-heterocyclic carbene copper(i) catalysed N-methylation of amines using CO2
Santoro, Orlando,Lazreg, Fama,Minenkov, Yury,Cavallo, Luigi,Cazin, Catherine S. J.
, p. 18138 - 18144 (2015/10/28)
The N-methylation of amines using CO2 and PhSiH3 as source of CH3 was efficiently performed using a N-heterocyclic carbene copper(i) complex. The methodology was found compatible with aromatic and aliphatic primary and secondary amines. Synthetic and computational studies have been carried out to support the proposed reaction mechanism for this transformation.
CO2 as a C1-building block for the catalytic methylation of amines
Jacquet, Olivier,Frogneux, Xavier,Das Neves Gomes, Christophe,Cantat, Thibault
, p. 2127 - 2131 (2013/05/21)
A novel catalytic reaction has been designed to utilize, for the first time, CO2 as a C1 feedstock in the synthesis of N-methylamines. Simple zinc catalysts, based on commercially available zinc salts and ligands, prove highly efficient in promoting both a 6 electron reduction of carbon dioxide and the formation of a C-N bond, using hydrosilanes and amines.