1031809-76-3

Basic information

• Product Name: O^5'-tert-butyldimethylsilyl-N⁶,N⁶,O^2',O^3'-tetrabenzoyladenosine
• Synonyms: O^5'-tert-butyldimethylsilyl-N⁶,N⁶,O^2',O^3'-tetrabenzoyladenosine
• CAS NO: 1031809-76-3
• Molecular Weight: 797.94
• Mol File: 1031809-76-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: O^5'-tert-butyldimethylsilyl-N⁶,N⁶,O^2',O^3'-tetrabenzoyladenosine(CAS DataBase Reference)
• NIST Chemistry Reference: O^5'-tert-butyldimethylsilyl-N⁶,N⁶,O^2',O^3'-tetrabenzoyladenosine(1031809-76-3)
• EPA Substance Registry System: O^5'-tert-butyldimethylsilyl-N⁶,N⁶,O^2',O^3'-tetrabenzoyladenosine(1031809-76-3)

Safety Data

• Hazardous Substances Data: 1031809-76-3(Hazardous Substances Data)

Upstream product

• 58-61-7 adenosine 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 1259874-82-2 C₄₃H₃₈N₅O₁₃P 
• 1260067-80-8 C₁₉H₂₀N₅O₁₀P 
• 58463-04-0 N6,N6,2'-O,3'-O-tetrabenzoyladenosine 

Relevant articles and documents

Design and synthesis of α-carboxy phosphononucleosides

Rhodium catalyzed O-H insertion reactions employing α- diazophosphonate 20 with appropriately protected thymidine, uridine, cytosine, adenosine and guanosine derivatives leads to novel 5′-phosphononucleoside derivatives. Deprotection led to a novel series of phosphono derivatives bearing a carboxylic acid moiety adjacent to the phosphonate group with potential antiviral and/or anticancer activity. The phosphononucleosides bearing an α-carboxylic acid group are envisaged as potential diphosphate mimics. Conversion to mono- and diphosphorylated phosphononucleosides has been effected for evaluation as nucleoside triphosphate mimics. Most of the novel phosphononucleosides proved to be inactive against a variety of DNA and RNA viruses. Only the phosphono AZT derivatives 56-59 showed weak activity against HIV-1 and HIV-2.