1031857-96-1 Usage
General Description
2,6-difluoro-4-(4,4,5,5-tetramethyl-1,3,2-bioxaborolan-2-yl)benzoic acid is a chemical compound used in organic synthesis. It contains a benzoic acid group as well as a 1,3,2-bioxaborolan-2-yl group, which contains boron. The presence of the boron group makes this compound useful in Suzuki-Miyaura coupling reactions, which are important in the formation of carbon-carbon bonds in organic molecules. 2,6-difluoro-4-(4,4,5,5-tetramethyl-1,3,2-bioxaborolan-2-yl)benzoic acid is particularly useful in the preparation of fluorinated pharmaceuticals and agrochemicals, as the fluorine substituents can enhance the biological activity of the resulting molecules. Additionally, the boron-containing group can also be utilized in the development of novel materials and as a building block in the design of organic electronic devices. Overall, 2,6-difluoro-4-(4,4,5,5-tetramethyl-1,3,2-bioxaborolan-2-yl)benzoic acid is a versatile and valuable compound in the field of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 1031857-96-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,3,1,8,5 and 7 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1031857-96:
(9*1)+(8*0)+(7*3)+(6*1)+(5*8)+(4*5)+(3*7)+(2*9)+(1*6)=141
141 % 10 = 1
So 1031857-96-1 is a valid CAS Registry Number.
1031857-96-1Relevant articles and documents
Synthesis and characterization of 2,6-difluoro-4-carboxyphenylboronic acid and a biotin derivative thereof as captors of anionic aqueous [18F]-fluoride for the preparation of [18F/19F]-labeled aryltrifluoroborates with high kinetic stability
Harwig, Curtis W.,Ting, Richard,Adam, Michael J.,Ruth, Thomas J.,Perrin, David M.
, p. 3152 - 3156 (2008/09/20)
Arylboronic esters are readily converted to aryltrifluoroborates in the presence of aqueous fluoride. As such these represent attractive synthetic precursors that afford one-step labeling with [18F]-fluoride for the generation of PET reagents. Herein we present the synthesis of a heretofore undisclosed arylboronic ester that is converted to its corresponding trifluoroborate. Essential for contemplating its use in PET imaging is the demonstration of kinetic resistance to solvolytic defluoridation.
