103258-06-6

Basic information

• Product Name: Benzamide, 2-formyl-N,N-bis(1-methylethyl)-
• CAS NO: 103258-06-6
• Molecular Formula: C14H19NO2
• Molecular Weight: 233.31
• Mol File: 103258-06-6.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Benzamide, 2-formyl-N,N-bis(1-methylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, 2-formyl-N,N-bis(1-methylethyl)-(103258-06-6)
• EPA Substance Registry System: Benzamide, 2-formyl-N,N-bis(1-methylethyl)-(103258-06-6)

Safety Data

• Hazardous Substances Data: 103258-06-6(Hazardous Substances Data)

Upstream product

• 20383-28-2 N,N-diisopropyl benzamide 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 1428732-55-1 2-((di-tert-butylphosphino)methyl)-N,N-diisopropylbenzamide hydrobromide 
• 220208-74-2 N,N-diisopropyl-o-allyloxymethylbenzamide 
• 354565-61-0 (2'S,4'S,5'R)-N,N-diisopropyl-2-[3,4-dimethyl-5-phenyl-1,3-oxazolan-2-yl]-6-(methylsulfanyl)benzamide 
• 354565-60-9 2-(3,4-dimethyl-5-phenyl-oxazolidin-2-yl)-6-formyl-N,N-diisopropyl-benzamide 
• 227201-66-3 6-methyl-2-[(methylimino)methyl]-N,N-diisopropyl-1-benzamide 
• 879899-78-2 N,N-diisopropyl-2-[(2R,4R,5S)-3,4-dimethyl-5-phenyloxazolidin-2-yl]-6-formylbenzamide 

Relevant articles and documents

Conformational arm-wrestling: Battles for stereochemical control in benzamides bearing matched and mismatched chiral 2- and 6-substituents

The orientation of a tertiary amide group adjacent to an aromatic ring may be governed by the stereochemistry of an adjacent chiral substituent. With a chiral substituent in both ortho positions, matched/mismatched pairs of isomers result. Evidence for ma

Phthalide: A direct building-block towards P,O and P,N hemilabile ligands. Application in the palladium-catalysed Suzuki-Miyaura cross-coupling of aryl chlorides

The direct synthesis of new hemilabile ligands from the economical, readily available lactone phthalide is described. Pd-complexes of one such ligand were found highly effective in general Suzuki-Miyaura cross-coupling reactions, including deactivated and hindered aryl chlorides. The Royal Society of Chemistry 2013.

Sparteine-mediated enantioselective [2,3]-Wittig rearrangement of allyl ortho-substituted benzyl ethers and ortho-substituted benzyl prenyl ethers

The (-)-sparteine-mediated enantioselective [2,3]-Wittig rearrangement of N,N-dialkyl-o-allyloxymethylbenzamides and o-substituted benzyl prenyl ethers has been investigated. Enantiomeric excess up to 60% was observed as for the reaction with N,N-diethyl-o-allyloxymetylbenzamide. From the mechanistic investigations, it was suggested that the stereoinformation was introduced at the deprotonation step. Substoichiometric amount of (-)- sparteine (0.2 equiv.) did not decrease the enantioselectivity. Introduction of functional groups other than carbamoyl group did not enhance the enantioselectivity in this rearrangement.