103262-35-7

Basic information

• Product Name: 2,3-DIHYDRO-1-BENZOFURAN-5-YLMETHANOL
• Synonyms: BUTTPARK 121\06-58;2,3-DIHYDRO-1-BENZOFURAN-5-YLMETHANOL;RARECHEM AL BD 0327;2,3-Dihydro-5-(hydroxymethyl)benzo[b]furan;(2,3-Dihydro-benzofuran-5-yl)-methanol;5-Hydroxymethyl-2,3-dihydrobenzo[b]furan;2,3-Dihydrobenzo[b]furan-5-yl Methanol;(2,3-Dihydro-1-benzofuran-5-yl)methanol, 2,3-Dihydro-5-(hydroxymethyl)-1-benzofuran
• CAS NO: 103262-35-7
• Molecular Formula: C₉H₁₀O₂
• Molecular Weight: 150.17
• Product Categories: Furan&Benzofuran
• Mol File: 103262-35-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 289.1 °C at 760 mmHg
• Flash Point: 137.7 °C
• Appearance: /
• Density: 1.217 g/cm³
• Vapor Pressure: 0.00104mmHg at 25°C
• Refractive Index: 1.5776 (589.3 nm 18℃)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 14.43±0.10(Predicted)
• CAS DataBase Reference: 2,3-DIHYDRO-1-BENZOFURAN-5-YLMETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-DIHYDRO-1-BENZOFURAN-5-YLMETHANOL(103262-35-7)
• EPA Substance Registry System: 2,3-DIHYDRO-1-BENZOFURAN-5-YLMETHANOL(103262-35-7)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-22
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 103262-35-7(Hazardous Substances Data)

Usage

General Description

2,3-Dihydro-1-benzofuran-5-ylmethanol, also known as DHBM, is a chemical compound with a molecular formula C9H10O2. It is a white to off-white solid with a melting point of 97-99°C. DHBM is commonly used in the synthesis of various pharmaceutical and agrochemical compounds, as well as in the production of fragrances and flavors. This chemical is also known for its potential biological activities, including anti-inflammatory and anticancer properties. DHBM is a versatile building block in organic synthesis and is widely used in the pharmaceutical and chemical industries.

InChI:InChI=1/C9H10O2/c10-6-7-1-2-9-8(5-7)3-4-11-9/h1-2,5,10H,3-4,6H2

Upstream product

• 76429-73-7 2,3-dihydrobenzofuran-5-carboxylic acid 
• 496-16-2 2.3-dihydrobenzofuran 
• 55745-70-5 2,3-dihydro-benzofuran-5-carbaldehyde 

Downstream Products

• 1353585-35-9 3-(2,3-dihydro-benzofuran-5-ylmethyl)-1-(4-methoxy-benzyl)-6-methylsulfanyl-1H-[1,3,5]triazine-2,4-dione 
• 55745-68-1 (2,3-dihydrobenzo[b]furan-5-yl)methyl chloride 
• 196598-26-2 5-bromomethyl-2,3-dihydrobenzofuran 

Relevant articles and documents

Benzopentaoxyheterocycle-benzimidazole salt compounds, and synthesis method and application thereof

The invention discloses benzopentaoxyheterocycle-benzimidazole salt compounds, and a synthesis method and an application thereof, and belongs to the technical field of medicinal chemistry. The structural formula of the benzopentaoxyheterocycle-benzimidazole salt compounds is shown in the description. In the formula, when X is O and Y is CH2, R and R are H, and R is a 2-naphthoylmethyl group, or R is CH3, R is H, and R is a 2-naphthoylmethyl group, a 4-bromobenzyl, a 2-naphthylmethyl group, a 4-methylbenzyl group or a 2-bromobenzyl group; when X is CH2 and Y is C-O, R and R are H, and R is a 2-naphthoylmethyl group, or R is CH3, R is H, and R is a 2-naphthoylmethyl group, or R is H, R is CH3, and R is a 2-naphthoylmethyl group or a 2-bromobenzylgroup; and when X is CH2 and Y is CH2, R is H, R is CH3, and R is a 2-naphthoylmethyl group or a 2-bromobenzyl group. Medicines prepared from the compounds of the invention and at least one pharmaceutically acceptable excipient, diluent or carrier can be used for tumor cancers.

Bicyclic compounds and pharmaceutical composition containing tricyclic compound for treating or preventing sleep disorders

A compound having the following general fomula: wherein R1 is an optionally substituted hydrocarbon, amino or heterocyclic group; R2 is H or an optionally substituted hydrocarbon group; R3 is H or an optionally substituted hydrocarbon or heterocyclic group; X is CHR4, NR4, O or S in which R4 is H or an optionally substituted hydrocarbon group; R5 is H, a halogen atom, C1-6 alkyl group, a C1-6 alkoxy group, a hydroxy group, a nitro group, a cyano group or an amino group wherein the C1-6 alkyl group, the C1-6 alkoxy group and the amino group may be substituted by 1 to 5 substituents, Y is C or N; ring B is an optionally substituted benzene ring; m = 1 to 4 and n = 0 to 2; L represents a leaving group such as a halogen atom, an alkylsulfonyl group, an alkylsulfonlyoxy group and arylsulfonyloxy group; or a salt thereof.

Tricyclic compounds, their production and use

A compound of the formula: STR1 wherein R1 is an optionally substituted hydrocarbon, amino or heterocyclic group; R2 is H or an optionally substituted hydrocarbon group; R3 is H or an optionally substituted hydrocarbon or heterocyclic group; X is CHR4, NR4, O or S in which R4 is H or an optionally substituted hydrocarbon group; Y is C, CH or N; ring A is optionally substituted 5- to 7-membered ring; ring B is an optionally substituted benzene ring; and m is 1 to 4, or a salt thereof, a process for producing it, an intermediate for the production and a pharmaceutical composition comprising it are provided.