103303-19-1Relevant articles and documents
A Tactically Novel Alternative to Acyclic Stereoselection Based on the Concept of a Replicating Chiron - 1,3- and 1,4-C-Methyl Substitution
Hanessian, Stephen,Murray, Peter J.,Sahoo, Soumya P.
, p. 5627 - 5630 (2007/10/02)
A chiral 4-hydroxymethyl butenolide is used as a template for the stereocontrolled conjugate addition of a C-methyl group.A sequential two-carbon extension and reformation of a lactone with the new side-chain leads to a "replicated" butenolide, which is s