103346-17-4Relevant articles and documents
Preparation method of meto-Iodobenzylguanidine
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Paragraph 0030; 0031, (2017/02/17)
The invention relates to a preparation method of I-MIBG (meto-Iodobenzylguanidine). The method comprises the following steps: heating meto-Iodobenzylguanidine sulfate, stannous mono-sulphate, a reducing agent, copper sulfate and NaI in a boiling water bath, standing after finishing the reaction, taking a supernatant liquid, and filtering the supernatant liquid with a microfiltration membrane. Sodium thiosulfate and/or sodium thiosulfate are/is taken as the reducing agent to prepare the meto-Iodobenzylguanidine sulfate, the prepared I-MIBG is high in radiochemical purity and good in stability, and the radiochemical purity of the prepared I-MIBG is still at a relatively high level after 48 hours.
STABILIZATION OF RADIOIODINATED AND ASTATINATED PHARMACEUTICALS AND IMAGING AGENTS
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Paragraph 0083; 0084, (2014/09/30)
Provided herein are stabilized radioiodinated and astatinated compounds, and to methods for their preparation.
Imaging agent and method of use
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, (2008/06/13)
A new radiopharmaceutical composition for use in nuclear medicine comprises a radioiodinated meta-iodobenzylguanidine. The composition is used as an imaging agent for the heart, adrenal medulla, and tumors of the adrenal medulla and can be used for treatm