1033747-90-8

Basic information

• Product Name: 2-Oxo-1,2-dihydroquinoline-7-carbonitrile
• Synonyms: 2-Oxo-1,2-dihydroquinoline-7-carbonitrile;2-Hydroxyquinoline-7-carbonitrile
• CAS NO: 1033747-90-8
• Molecular Formula: C10H6N2O
• Molecular Weight: 170.17
• Mol File: 1033747-90-8.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Oxo-1,2-dihydroquinoline-7-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Oxo-1,2-dihydroquinoline-7-carbonitrile(1033747-90-8)
• EPA Substance Registry System: 2-Oxo-1,2-dihydroquinoline-7-carbonitrile(1033747-90-8)

Safety Data

• Hazardous Substances Data: 1033747-90-8(Hazardous Substances Data)

Usage

General Description

2-Oxo-1,2-dihydroquinoline-7-carbonitrile is a chemical compound which belongs to the class of organic compounds known as quinolines and derivatives. Quinolines and their derivatives are compounds containing a quinoline moiety, a structure characterized by a benzene ring fused to a pyridine ring forming a benzo[g]quinoline skeleton. This particular compound is characterized by a 2-oxo-1,2-dihydroquinoline group attached to a cyano group at the seventh carbon position. Little information is available regarding its chemical applications or potential human health implications. As a scientific reagent, it would likely be stored under specific conditions to prevent degradation and used primarily in lab-based research or industrial chemical reactions. The physical, toxicological and ecological properties of this chemical are not fully studied or recorded in literature.

Upstream product

• 105191-34-2 3-(4-cyano-2-nitro-phenyl)-2-oxo-propionic acid ethyl ester 
• 22246-18-0 7-hydroxy-3,4-dihydro-2-(1H)-quinolinone 
• 903557-01-7 2-oxo-1,2,3,4-tetrahydroquinoline-7-carbonitrile 
• 882023-50-9 2-oxo-1,2,3,4-tetrahydroquinolin-7-yl trifluoromethanesulfonate 
• 104-85-8 para-methylbenzonitrile 
• 939-79-7 4-cyano-2-nitrotoluene 
• 1033747-92-0 3-hydroxy-2-oxo-1,2,3,4-tetrahydro-quinoline-7-carbonitrile 
• 99465-10-8 7-bromo-1,2-dihydroquinolin-2-one 

Relevant articles and documents

Oxidative Aromatization of 3,4-Dihydroquinolin-2(1 H)-ones to Quinolin-2(1 H)-ones Using Transition-Metal-Activated Persulfate Salts

Inorganic persulfate salts were identified as efficient reagents for the oxidative aromatization of 3,4-dihydroquinolin-2(1H)-ones through the activation of readily available transition metals, such as iron and copper. The feasible protocol conforming to the requirement of green chemistry was utilized in the preparation of the key intermediate (7-(4-chlorobutoxy)quinolin-2(1H)-one 2) of brexpiprazole in 80% isolated yield on a 100 g scale, and different quinolin-2(1H)-one derivatives with various functional groups were demonstrated in 52-89% yields.

INHIBITORS OF DNA GYRASE FOR THE TREATMENT OF BACTERIAL INFECTIONS

The present invention relates to compounds which specifically inhibit bacterial DNA Gyrase and can be used for the treatment of respiratory tract infections.

2-QUINOLINONE AND 2-QUINOXALINONE- DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS

The present invention relates to compounds of Formula (I) : and pharmaceutically acceptable salts thereof, to their use in the treatment of bacterial infections, and to their methods of preparation.