103383-78-4

Basic information

• Product Name: 5-Hexen-2-one, 3-hydroxy-3-phenyl-, (R)-
• CAS NO: 103383-78-4
• Molecular Formula: C12H14O2
• Molecular Weight: 190.242
• Mol File: 103383-78-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-Hexen-2-one, 3-hydroxy-3-phenyl-, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Hexen-2-one, 3-hydroxy-3-phenyl-, (R)-(103383-78-4)
• EPA Substance Registry System: 5-Hexen-2-one, 3-hydroxy-3-phenyl-, (R)-(103383-78-4)

Safety Data

• Hazardous Substances Data: 103383-78-4(Hazardous Substances Data)

Upstream product

• 917-54-4 methyllithium 
• 103383-73-9 (3R,8aS)-3-phenyl-3-(2-propenyl)-1,4-dioxo-3,4,6,7,8,8a-hexahydro-1H-pyrrolo<2,1-c><1,4>oxazine 
• 103383-75-1 (S)-1-(2-Hydroxy-2-phenyl-pent-4-enoyl)-pyrrolidine-2-carboxylic acid isopropyl ester 
• 97409-50-2 isopropyl (S)-N-(benzoylformyl)prolinate 
• 2114-00-3 2-bromo-1-phenyl-1-propanone 
• 925462-06-2 carbonic acid allyl ester (E)-2-(tert-butyl-dimethyl-silanyloxy)-1-methyl-2-phenyl-vinyl ester 
• 925462-16-4 (R)-(+)-3-(tert-butyl-dimethyl-silanyloxy)-3-phenyl-hex-5-en-2-one 

Relevant articles and documents

Enantioselective synthesis of α-tertiary hydroxyaldehydes by palladium-catalyzed asymmetric allylic alkylation of enolates

Chiral α-tertiary hydroxyaldehydes are very versatile building blocks in synthetic chemistry. Herein, we report the first examples of a catalytic asymmetric protocol for the synthesis of such compounds from readily available α-halo or α-hydroxy ketones or enol silyl ethers with excellent yields and enantioselectivity. Its synthetic utility is demonstrated in the short, efficient formal synthesis of (S)-oxybutynin. In this process, the chiral ligand controls the regioselectivity as well as the enantioselectivity. Copyright