103404-70-2 Usage
Description
3-Deoxy-D-manno-2-octulosonic acid ammonium salt (KDO) is a ketosidic component found in all lipopolysaccharides of Gram-negative bacteria and has been identified in several acidic exopolysaccharides (K-antigens). It is a white crystalline solid with significant potential in the field of antibacterial research.
Uses
Used in Pharmaceutical Industry:
3-Deoxy-D-manno-2-octulosonic acid ammonium salt is used as a key component in the development of new antibacterial agents. The reason for its application is its presence in lipopolysaccharides of Gram-negative bacteria, which makes it a potential target for disrupting the biosynthesis of bacterial cell-wall components.
Used in Research and Development:
3-Deoxy-D-manno-2-octulosonic acid ammonium salt is used as a subject of study for the development of synthetic analogues. The application reason is to explore their potential in disrupting bacterial cell-wall biosynthesis, which could lead to the creation of innovative antibacterial agents.
Used in Bacterial Pathogenesis Studies:
3-Deoxy-D-manno-2-octulosonic acid ammonium salt is used as a research tool to understand the pathogenesis of Gram-negative bacteria. The application reason is its role in the structure of lipopolysaccharides and K-antigens, which are crucial for the survival and virulence of these bacteria.
Biochem/physiol Actions
KDO is a sialic acid that is a component of bacterial lipopolysaccharides and a possible target for antibiotic development.
Check Digit Verification of cas no
The CAS Registry Mumber 103404-70-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,3,4,0 and 4 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 103404-70:
(8*1)+(7*0)+(6*3)+(5*4)+(4*0)+(3*4)+(2*7)+(1*0)=72
72 % 10 = 2
So 103404-70-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H14O8.H3N/c9-2-5(12)7(14)6(13)3(10)1-4(11)8(15)16;/h3,5-7,9-10,12-14H,1-2H2,(H,15,16);1H3
103404-70-2Relevant articles and documents
Structural Analogs of 2-Keto-3-deoxy-D-mannooctulosonic Acid
Sengupta, Dibyendu,Cherniak, Robert
, p. 85 - 87 (2007/10/02)
The synthesis of 3-deoxy sugars (4-8) has been carried out as structural analogs of 2-keto-3-deoxy-D-mannooctulosonic acid (KDO; 1).
