1034094-54-6 Usage
Description
2-(3-trifluoromethylphenyl)propanal is an organic compound with the molecular formula C10H9F3O. It is characterized by its distinct chemical structure, which features a propanal group (a three-carbon aldehyde chain) attached to a phenyl ring substituted with a trifluoromethyl group at the meta position.
Uses
Used in Pharmaceutical Industry:
2-(3-trifluoromethylphenyl)propanal is used as an impurity in the drug Cinacalcet (C441800) for its role as a calcimimetic agent. It targets the calcium-sensing receptor to lower parathyroid hormone (PTH), calcium, and phosphorus levels in patients with secondary hyperparathyroidism (SHPT). This application is crucial for managing the symptoms and complications associated with SHPT, making it a valuable component in the pharmaceutical sector.
Check Digit Verification of cas no
The CAS Registry Mumber 1034094-54-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,3,4,0,9 and 4 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1034094-54:
(9*1)+(8*0)+(7*3)+(6*4)+(5*0)+(4*9)+(3*4)+(2*5)+(1*4)=116
116 % 10 = 6
So 1034094-54-6 is a valid CAS Registry Number.
1034094-54-6Relevant articles and documents
Direct Synthesis of α-Allenols from TMS-Protected Alkynes and Aldehydes Mediated by Tetrabutylammonium Fluoride
Huang, Xiaojun,Bugarin, Alejandro
supporting information, p. 12696 - 12700 (2016/08/30)
A unique chemoselective synthesis of α-allenic alcohols is presented. Tetrabutylammonium fluoride (TBAF) mediated this transformation under mild reaction conditions. A range of functional groups is well-tolerated in this reaction, while affording adducts
Supramolecular control of selectivity in hydroformylation of vinyl arenes: Easy access to valuable β-aldehyde intermediates
Dydio, Pawel,Reek, Joost N. H.
supporting information, p. 3878 - 3882 (2013/05/09)
Go against the flow! A rationally designed regioselective hydroformylation catalyst, [Rh/L], in which noncovalent ligand-substrate interactions allow the unprecedented reversal of selectivity from the typical α-aldehyde to the otherwise unfavored product β-aldehyde, is reported. This catalytic system opens up novel and sustainable synthetic pathways to important intermediates for the fine-chemicals industry.
