103437-70-3Relevant articles and documents
Easy Access to 5-(E)-Alkynylidene Tetrahydro-2 Furanones by a Palladium Catalyzed Process
Bouyssi, Didier,Gore, Jacques,Balme, Genevieve
, p. 2811 - 2814 (1992)
Biologically active ynenol lactones 1 are stereospecifically obtained when γ-acetylenic carboxylates are reacted with 1-bromo 1-alkynes in the presence of a palladium(0)-phosphine complex.The reaction is effective only with the potassium carboxylate and the nature of the phosphine is essential for the cyclisation process.