103440-91-1

Basic information

• Product Name: 1-(2-Hydroxy-4-methyl-5-nitrophenyl)ethanone
• Synonyms: 1-(2-Hydroxy-4-methyl-5-nitrophenyl)ethanone
• CAS NO: 103440-91-1
• Molecular Weight: 195.175
• Mol File: 103440-91-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-(2-Hydroxy-4-methyl-5-nitrophenyl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-Hydroxy-4-methyl-5-nitrophenyl)ethanone(103440-91-1)
• EPA Substance Registry System: 1-(2-Hydroxy-4-methyl-5-nitrophenyl)ethanone(103440-91-1)

Safety Data

• Hazardous Substances Data: 103440-91-1(Hazardous Substances Data)

Upstream product

• 2581-34-2 3-methyl-4-nitrophenol 
• 79139-40-5 3-methyl-4-nitrophenyl acetate 
• 6921-64-8 4'-hydroxy-2'-methylacetophenone 

Relevant articles and documents

Synthesis and in-vitro evaluation of platelet aggregation inhibitory activity of paeonol and its analogues

Paeonol (1-(2-hydroxy-4-methoxyphenyl)ethanone) and a series of substituted 1-(2-hydroxyphenyl)ethanone derivatives were synthesized and screened as inhibitors of platelet aggregation. The compounds with the greatest anti-platelet potential among the series tested were 1-(2,5-dihydroxyphenyl)ethanone (65.36% inhibition at 300 μM against 5 μM ADP), paeonol(36.31%), 1-(2-hydroxy-5-methoxyphenyl)ethanone (24.47%), 1-(2-hydroxy-5-nitrophenyl) ethanone (30.40%) and 1-(5-chloro-2-hydroxy-4-methylphenyl)ethanone (24.43%).

Polysubstituted heterocyclic derivative, preparation method thereof and application of polysubstituted heterocyclic derivative in medicine

The invention provides a polysubstituted heterocyclic derivative, a preparation method thereof and application of the polysubstituted heterocyclic derivative in medicine, and belongs to the technical field of medicinal chemistry. The polysubstituted heterocyclic derivative is a compound shown in a general formula I or II, a pharmaceutically acceptable salt or a solvate of the compound, and the compound can inhibit mRNA demethylase on the protease level and is used for treating diseases related to mRNA demethylase functions.