1034621-77-6Relevant articles and documents
Catalytic ortho -acetoxylation of masked benzyl alcohols via an exo -directing mode
Ren, Zhi,Schulz, Jonathan E.,Dong, Guangbin
supporting information, p. 2696 - 2699 (2015/06/16)
A Pd-catalyzed ortho-acetoxylation of masked benzyl alcohols to synthesize various 2-hydroxyalkylphenol derivatives is reported. The 2,6-dimethoxyl benzaldoxime proved to be an efficient exo-type directing group for arene (sp2) C-H functionalization. Two strategies were demonstrated to remove the directing group through N-O and C-O bond cleavages. A high catalyst turnover (>1000) was obtained to illustrate the practicality of this method.