1034689-05-8

Basic information

• Product Name: 1-methylethyl 3-bromo-4-[(1-methylethyl)oxy]benzoate
• Synonyms: 1-methylethyl 3-bromo-4-[(1-methylethyl)oxy]benzoate
• CAS NO: 1034689-05-8
• Molecular Weight: 301.18
• Mol File: 1034689-05-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-methylethyl 3-bromo-4-[(1-methylethyl)oxy]benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methylethyl 3-bromo-4-[(1-methylethyl)oxy]benzoate(1034689-05-8)
• EPA Substance Registry System: 1-methylethyl 3-bromo-4-[(1-methylethyl)oxy]benzoate(1034689-05-8)

Safety Data

• Hazardous Substances Data: 1034689-05-8(Hazardous Substances Data)

Upstream product

• 75-30-9 2-iodo-propane 
• 14348-41-5 3-bromo-4-hydroxy-benzoic acid 
• 75-26-3 isopropyl bromide 

Downstream Products

• 213598-20-0 3-Bromo-4-iso-propoxybenzoic Acid 
• 1261173-10-7 1-methylethyl 3-cyano-4-[(1-methylethyl)oxy]benzoate 
• 258273-31-3 3-cyano-4-isopropoxybenzoic acid 
• 1174512-20-9 tert-butyl 2-(7-(5-(3-cyano-4-isopropoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-yl)acetate 

Relevant articles and documents

DISUBSTITUTED OXADIAZOLE DERIVATIVES USEFUL IN THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISORDERS

The present invention relates to certain disubstituted oxadiazole derivatives of Formula (Ia) and pharmaceutically acceptable salts, solvates, and hydrates thereof, which exhibit useful pharmacological properties, for example, as agonists of the S1P1 receptor. Also provided by the present invention are pharmaceutical compositions containing compounds of the invention, and methods of using the compounds and compositions of the invention in the treatment of S1P1-associated disorders, for example, psoriasis, rheumatoid arthritis, Crohn's disease, transplant rejection, multiple sclerosis, systemic lupus erythematosus, ulcerative colitis, type I diabetes, acne, myocardial ischemia-reperfusion injury, hypertensive nephropathy, glomerulosclerosis, gastritis, polymyositis, thyroiditis, vitiligo, hepatitis, biliary cirrhosis, microbial infections and associated diseases, viral infections and associated diseases, diseases and disorders mediated by lymphocytes, auto immune diseases, inflammatory diseases, and cancer.

OXADIAZOLE SUBSTITUTED INDAZOLE DERIVATIVES FOR USE AS SPHINGOSINE 1-PHOSPHATE (S1P) AGONISTS

The present invention provides compounds of formula (I) or salts thereof, having pharmacological activity, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders mediated by S1P1 receptors.