10347-01-0

Basic information

• Product Name: 1,3-DIMETHYLADAMANTANE-5,7-DIOL
• Synonyms: 1,3-DIMETHYLADAMANTANE-5,7-DIOL;AKOS BC-0469;5,7-DIMETHYL-1,3-ADAMANTANEDIOL;1,3-dihydroxy-5,7-dimethyladamantane
• CAS NO: 10347-01-0
• Molecular Formula: C₁₂H₂₀O₂
• Molecular Weight: 196.29
• Mol File: 10347-01-0.mol
• Article Data: 13

Chemical Properties

• Melting Point: 214-215 °C
• Boiling Point: 310.4±10.0 °C(Predicted)
• Appearance: /
• Density: 1.287±0.06 g/cm3(Predicted)
• PKA: 14.68±0.70(Predicted)
• CAS DataBase Reference: 1,3-DIMETHYLADAMANTANE-5,7-DIOL(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-DIMETHYLADAMANTANE-5,7-DIOL(10347-01-0)
• EPA Substance Registry System: 1,3-DIMETHYLADAMANTANE-5,7-DIOL(10347-01-0)

Safety Data

• Hazardous Substances Data: 10347-01-0(Hazardous Substances Data)

Usage

General Description

1,3-Dimethyladamantane-5,7-diol is a chemical compound with a molecular formula of C12H20O2. It is a derivative of adamantane, a bicyclic hydrocarbon, and contains two methyl groups and two hydroxyl groups. 1,3-DIMETHYLADAMANTANE-5,7-DIOL is a chiral molecule, meaning it exists in two enantiomeric forms. 1,3-Dimethyladamantane-5,7-diol has potential pharmacological applications and may be used in medicinal chemistry for the development of new drugs. It is important to handle this chemical with caution as its effects and safety profile need to be thoroughly researched and evaluated.

Upstream product

• 624-48-6 dimethyl cis-but-2-ene-1,4-dioate 
• 524-38-9 N-hydroxyphthalimide 
• 702-79-4 1,3-dimethyladamantane 
• 19982-07-1 1-acetamido-3,5-dimethyladamantane 
• 101821-77-6 3,5-dimethyladamantan-1-yl nitrate 
• 13928-68-2 5,7-dimethyladamantane-1,3-dicarboxylic acid 
• 101821-80-1 5,7-dimethyl-1,3-adamantanediol dinitrate 

Downstream Products

• 17768-33-1 5,7-Dichlor-1,3-dimethyl-adamantan 
• 17837-78-4 2,2'-(5,7-dimethyladamantylene-1,3)diethanoic acid 
• 26424-46-4 1,3-bis(4-hydroxyphenyl)-5,7-dimethyladamantane 
• 20366-07-8 1,3-Diacetoxy-5,7-dimethyl-adamantan 

Relevant articles and documents

One-pot synthesis of cage alcohols

An efficient one-pot procedure has been developed for the synthesis of cage alcohols with hydroxy groups in the bridgehead positions. The procedure includes initial nitroxylation with nitric acid or a mixture of nitric acid with acetic acid and subsequent hydrolysis in the presence of urea.

Synthesis of hydroxy derivatives from adamantanecarboxylic acids in the system MnO2–H2SO4

A convenient procedure has been developed for the synthesis of mono- and dihydric cage alcohols from adamantanecarboxylic acids and their esters using the MnO2–H2SO4system. The reaction at elevated temperature involved both decarboxylation and decarbonylation of the initial acid or ester.

Malic acid and oxalacetic acid derivatives

A malic acid or oxalacetic acid derivative is represented by the following formula (1): wherein ring Z is an alicyclic carbon ring; each of Ra and Rb is independently a hydrogen atom, a metal atom, or an organic group; and Y is a hydroxyl group or an oxygen atom, where ring Z is a bridged carbon ring or a monocyclic carbon ring having eight or more members when Y is an oxygen atom. The alicyclic carbon ring includes, for example, cyclooctane ring and adamantane ring. This compound is a novel malic acid derivative having an alicyclic group bonded to a carbon atom at the 3-position, or a novel oxalacetic acid derivative having a specific alicyclic group bonded to a carbon atom at the 3-position.