103493-12-5

Basic information

• Product Name: N¹,N⁸-bis(benzyloxycarbonyl)spermine
• Synonyms: N¹,N⁸-bis(benzyloxycarbonyl)spermine
• CAS NO: 103493-12-5
• Molecular Weight: 470.612
• Mol File: 103493-12-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N¹,N⁸-bis(benzyloxycarbonyl)spermine(CAS DataBase Reference)
• NIST Chemistry Reference: N¹,N⁸-bis(benzyloxycarbonyl)spermine(103493-12-5)
• EPA Substance Registry System: N¹,N⁸-bis(benzyloxycarbonyl)spermine(103493-12-5)

Safety Data

• Hazardous Substances Data: 103493-12-5(Hazardous Substances Data)

Upstream product

• 13139-17-8 N-(Benzyloxycarbonyloxy)succinimide 
• 71-44-3 Spermine 
• 28170-07-2 benzyl phenyl carbonate 
• 194808-59-8 N⁴,N⁹-di(tert-butyloxycarbonyl)-3-(4-[(2-cyanoethyl)amino]butylamino)propanenitrile 
• 177213-61-5 di-tert-butyl butane-1,4-diylbis((3-aminopropyl)carbamate) 
• 14209-32-6 3-(4-[(2-cyanoethyl)amino]butylamino)propanenitrile 
• 221226-22-8 (3-benzyloxycarbonylamino-propyl)-{4-[(3-benzyloxycarbonylamino-propyl)-tert-butoxycarbonyl-amino]-butyl}-carbamic acid tert-butyl ester 

Relevant articles and documents

Selective synthesis of carbamate protected polyamines using alkyl phenyl carbonates

Utilising alkyl phenyl carbonates, an economical, practical and versatile method for selective Boc, Cbz and Alloc protection of polyamines has been developed. This method allows Boc, Cbz and Alloc protection of primary amines in the presence of secondary amines by reaction of the polyamines with the alkyl phenyl carbonates. Also, this method allows mono carbamate protection of simple symmetrical aliphatic α,ω-alkanediamines in high yields with respect to the diamine. Finally, the method allows selective carbamate protection of a primary amine located on a primary carbon in the presence of a primary amine located on a secondary or a tertiary carbon in excellent yields.

Chemoselective synthesis of protected polyamines and facile synthesis of polyamine derivatives using O-alkyl-O′-(N-succinimidyl) carbonates

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