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103521-70-6

103521-70-6

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103521-70-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 103521-70-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,3,5,2 and 1 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 103521-70:
(8*1)+(7*0)+(6*3)+(5*5)+(4*2)+(3*1)+(2*7)+(1*0)=76
76 % 10 = 6
So 103521-70-6 is a valid CAS Registry Number.

103521-70-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name (+/-)-Mebudipine

1.2 Other means of identification

Product number -
Other names tert-butyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:103521-70-6 SDS

103521-70-6Relevant articles and documents

Stereochemical requirements for the mineralocorticoid receptor antagonist activity of dihydropyridines

Arhancet, Graciela B.,Woodard, Scott S.,Dietz, Jessica D.,Garland, Danny J.,Wagner, Grace M.,Iyanar, Kaliappan,Collins, Joe T.,Blinn, James R.,Numann, Randal E.,Hu, Xiao,Huang, Horng-Chih

supporting information; experimental part, p. 4300 - 4304 (2010/08/22)

A number of known 1,4-dihydropyridine CCBs were identified as having comparable potency to the steroidal MR antagonist eplerenone. Chiral resolution of mebudipine revealed that MR and CCB activity reside in opposite enantiomers. Small molecule X-ray crystal structures showed that the C4 stereochemistry of optimized selective MR analogues, e.g. 5, is consistent with MR-active mebudipine. Molecular modeling supports a binding pose consistent with that previously proposed for DHP diesters.

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