1037074-17-1

Basic information

• Product Name: (S)-(4-Methoxy-phenyl)-{[1-phenyl-meth-(Z)-ylidene]-amino}-acetonitrile
• CAS NO: 1037074-17-1
• Molecular Weight: 250.3
• Mol File: 1037074-17-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-(4-Methoxy-phenyl)-{[1-phenyl-meth-(Z)-ylidene]-amino}-acetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(4-Methoxy-phenyl)-{[1-phenyl-meth-(Z)-ylidene]-amino}-acetonitrile(1037074-17-1)
• EPA Substance Registry System: (S)-(4-Methoxy-phenyl)-{[1-phenyl-meth-(Z)-ylidene]-amino}-acetonitrile(1037074-17-1)

Safety Data

• Hazardous Substances Data: 1037074-17-1(Hazardous Substances Data)

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 85803-46-9 (R)-N-(p-Methoxybenzylidene)-2-amino-2-phenylethanol 
• 56613-80-0 D-2-phenylglycinol 
• 139224-89-8 N-<(R)-2-hydroxy-1-phenylethyl>-(S)-α-amino-4-methoxybenzeneacetonitrile 

Downstream Products

• 24593-48-4 (2S)-2-amino-2-(4-methoxyphenyl)acetic acid 

Relevant articles and documents

A simple and efficient diastereoselective Strecker synthesis of optically pure α-arylglycines

A simple and economical method for the synthesis of highly functionalised α-amino nitriles, precursors to α-arylglycines with high optical purity is reported. For this purpose, (R) or (S)-2-amino-2- phenylethanol were used as chiral auxiliaries in a 1,3 Strecker reaction. Reactions were studied with a broad range of reagent systems for the generation of cyano nucleophile. Methodology has been extended for the synthesis of (S)-α-(2-iodo-5-nitrophenyl)glycine, (S)-α-(4- methoxyphenyl)glycine and (R)-β-(4-methoxyphenyl)alanine.