103754-13-8

Basic information

• Product Name: ethyl m-chlorophenylimidoacetate hydrochloride
• Synonyms: ethyl m-chlorophenylimidoacetate hydrochloride
• CAS NO: 103754-13-8
• Molecular Weight: 234.125
• Mol File: 103754-13-8.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: ethyl m-chlorophenylimidoacetate hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl m-chlorophenylimidoacetate hydrochloride(103754-13-8)
• EPA Substance Registry System: ethyl m-chlorophenylimidoacetate hydrochloride(103754-13-8)

Safety Data

• Hazardous Substances Data: 103754-13-8(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 1529-41-5 3-chloro-benzeneacetonitrile 

Downstream Products

• 1273315-64-2 2-(3-chlorobenzyl)-9-methyl-7,9-dihydro-8H-purine-8-one 
• 1273315-60-8 ethyl 2-(3-chlorobenzyl)-4-(methylamino)pyrimidine-5-carboxylate 
• 1273315-62-0 2-(3-chlorobenzyl)-4-(methylamino)pyrimidine-5-carboxylate 
• 6487-96-3 2-(3-chlorophenyl)ethaneimidamide hydrochloric acid salt 
• 1616422-60-6 N'-[2-(3-chlorophenyl)ethanimidoyl]-2-phenylacetohydrazide 
• 1616422-74-2 N-[2-(3-chlorobenzyl)-4-(4-chlorophenyl)-1H-imidazol-1-yl]-2-phenylacetamide 
• 1616422-67-3 N-[2-(3-chlorobenzyl)-4-phenyl-1H-imidazol-1-yl]-2-phenylacetamide 
• 1470364-75-0 5-(m-chlorobenzyl)-4-p-nitrobenzyliden amino-2,4-dihydro-2H-1,2,4-triazol-3-one 
• 1470364-74-9 5-(m-chlorobenzyl)-4-p-fluorobenzyliden amino-2,4-dihydro-2H-1,2,4-triazol-3-one 
• 1443550-81-9 5,6-dichloro-2-(3-chlorobenzyl)-1H-benzimidazole 
• 1443550-92-2 2-[5,6-dichloro-2-(3-chlorobenzyl)-1H-benzimidazol-1-yl]acetic acid hydrazide 
• 1443550-86-4 methyl 2-[5,6-dichloro-2-(3-chlorobenzyl)-1H-benzimidazol-1-yl]acetate 
• 1450838-38-6 phenyl[2-(3-chlorobenzyl)-1H-1,3-benzimidazol-5-yl]methanone 

Relevant articles and documents

Synthesis of Some Novel 2-Substitutedbenzyl-(4)7-phenyl-1H-benzo[d]imidazoles in Mild Conditions as Potent Anti-Tyrosinase and Antioxidant Agents

Novel 2-substitutedbenzyl-4(7)-phenyl-1H-benzo[d]imidazole compounds were synthesized and characterized. Although 2a and 2b were reported previously in the literature, 11 compounds were synthesized (nine of them were newly synthesized) and the tyrosinase inhibitory effects and antioxidant activities of these compounds were studied for the first time. All of the synthesized compounds displayed certain inhibitory effects on tyrosinase, with IC50 values ranging from 37.86 ± 0.24 to 75.81 ± 2.49 μM. Among the compounds, 2j exhibited similar tyrosinase inhibitory effect (IC50 = 37.86 ± 0.24 μM) to the positive control, kojic acid (IC50 = 21.93 ± 0.11 μM). Kinetic studies revealed it to act as non-competitive tyrosinase inhibitor with a Ki value of 50.2 μM. The antioxidant activities of the compounds were investigated by using in vitro antioxidant assays, including 2,2-diphenyl-1-picrylhydrazyl (DPPH) and ferric reducing antioxidant power (FRAP). All of these results indicated that the compounds might have potential application as tyrosinase inhibitors.

Microwave-assisted synthesis of some 5(6)-nitro-1H-benzimidazoles and their hydrazide derivatives

A series of 5(6)-nitro-1H-benzimidazole and their hydrazide derivatives were synthesized starting from iminoester hydrochloride and 4-nitro-o- phenylenediamine under microwave irradiation. The structure of all synthesized compounds was confirmed by IR, s

Microwave-assisted synthesis of some new benzylidenamino compounds and potentiometric determination of their pKa

A growing body of literature has shown the effectiveness of using microwaves in chemical reactions. The aim of this study is to demonstrate a rapid and highly efficient synthesis of some new benzylidenamino compounds (4a-f) via microwave heating using a m