1037597-71-9

Basic information

• Product Name: ethyl 2-(p-tolyl)oxazole-5-carboxylate
• Synonyms: ethyl 2-(p-tolyl)oxazole-5-carboxylate
• CAS NO: 1037597-71-9
• Molecular Weight: 231.251
• Mol File: 1037597-71-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: ethyl 2-(p-tolyl)oxazole-5-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-(p-tolyl)oxazole-5-carboxylate(1037597-71-9)
• EPA Substance Registry System: ethyl 2-(p-tolyl)oxazole-5-carboxylate(1037597-71-9)

Safety Data

• Hazardous Substances Data: 1037597-71-9(Hazardous Substances Data)

Upstream product

• 106-38-7 para-bromotoluene 
• 118994-89-1 oxazol-5-yl-carboxylic acid ethyl ester 
• 36719-51-4 3,3-diethyl-1-(4-methylphenyl)-1-triazene 
• 25563-06-8 N-methoxy-4-methylbenzamide 

Relevant articles and documents

Direct Arylation of Azoles Enabled by Pd/Cu Dual Catalysis

A practical approach toward the synthesis of 2-arylazoles via direct arylation is described. The transformation relies on a Pd/Cu cocatalyst system that operates with low catalyst loadings. The reaction conditions were found to be tolerant of a wide range of functional groups and nitrogen-containing heterocycles commonly employed in a drug discovery setting.

Palladium-catalyzed deamidative arylation of azoles with arylamides through a tandem decarbonylation-C-H functionalization

A highly chemo-, regio-selective, and efficient palladium-catalyzed deamidative arylation of azoles with arylamides, as an aryl metal equivalent, has been developed. The reaction proceeds smoothly to generate the corresponding products in good yields via a tandem decarbonylation-C-H activation.