103772-14-1 Usage
Description
5-Amino-1-Cyclopropyl-6,7,8-Trifluoro-1,4-Dihydro-4-Oxo-3-Quinolinearboxylic Acid is a chemical compound that is identified as an impurity in Sparfloxacin (S679250), a fluorinated quinolone antibacterial agent. 5-Amino-l-Cyclopropyl-6,7, 8-Trifluoro-1,4-Dihydro-4-Oxo-3-Quinolinearboxylic Acid is characterized by its unique molecular structure, which includes a cyclopropyl group, a quinoline core, and trifluoro substituents.
Uses
Used in Pharmaceutical Industry:
5-Amino-1-Cyclopropyl-6,7,8-Trifluoro-1,4-Dihydro-4-Oxo-3-Quinolinearboxylic Acid is used as an impurity in the production of Sparfloxacin (S679250), a fluorinated quinolone antibacterial agent. The presence of this compound in the manufacturing process of Sparfloxacin is significant as it can impact the overall quality, safety, and efficacy of the final product. As a result, monitoring and controlling the levels of this impurity are crucial for ensuring the therapeutic benefits and minimizing potential side effects of the antibacterial drug.
In the context of pharmaceutical development, understanding the properties and effects of impurities like 5-Amino-1-Cyclopropyl-6,7,8-Trifluoro-1,4-Dihydro-4-Oxo-3-Quinolinearboxylic Acid is essential for optimizing the manufacturing process and ensuring the safety and efficacy of the final drug product. This knowledge can also be applied to the development of new drugs or the improvement of existing ones, potentially leading to more effective treatments for various bacterial infections.
Check Digit Verification of cas no
The CAS Registry Mumber 103772-14-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,3,7,7 and 2 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 103772-14:
(8*1)+(7*0)+(6*3)+(5*7)+(4*7)+(3*2)+(2*1)+(1*4)=101
101 % 10 = 1
So 103772-14-1 is a valid CAS Registry Number.
InChI:InChI=1/C13H9F3N2O3/c14-7-8(15)10(17)6-11(9(7)16)18(4-1-2-4)3-5(12(6)19)13(20)21/h3-4H,1-2,17H2,(H,20,21)
103772-14-1Relevant articles and documents
QUINOLIN-4-ONE AND 4(1H)-CINNOLINONE COMPOUNDS AND METHODS OF USING SAME
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, (2020/08/22)
The present disclosure relates to quinolin-4-one and 4(1H)-cinnolinone compounds and methods of using them to induce self-renewal of stem/progenitor supporting cells, including inducing the stem/progenitor cells to proliferate while maintaining, in the daughter cells, the capacity to differentiate into tissue cells.
Aminoquinolones as GSK-3 inhibitors
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Page/Page column 91; 92, (2008/06/13)
Provided herein are aminoquinolones and pharmaceutically acceptable derivatives thereof. In certain embodiments, provided herein are compounds, compositions and methods for treating, preventing or ameliorating GSK-3 mediated diseases.
Quinoline derivatives and processes for preparation thereof
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, (2008/06/13)
The present invention relates to a quinoline derivative of the formula wherein Z is an amino group or a halogen atom, R1 is a hydrogen atom or a methyl or ethyl group, R2 is a hydrogen atom or a methyl or fluoromethyl group, R3 and R4 are the same or different and each represents a hydrogen atom or a methyl group, and n is 1 or 2; and esters thereof and salts thereof and processes for preparation thereof. These compounds show excellent antibacterial activity and are useful antibacterial agents
