1037826-43-9

Basic information

• Product Name: N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-2-(3-phenyl-1H-pyrazol-1-yl)nicotinamide
• CAS NO: 1037826-43-9
• Molecular Weight: 439.473
• Mol File: 1037826-43-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-2-(3-phenyl-1H-pyrazol-1-yl)nicotinamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-2-(3-phenyl-1H-pyrazol-1-yl)nicotinamide(1037826-43-9)
• EPA Substance Registry System: N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-2-(3-phenyl-1H-pyrazol-1-yl)nicotinamide(1037826-43-9)

Safety Data

• Hazardous Substances Data: 1037826-43-9(Hazardous Substances Data)

Upstream product

• 6372-14-1 N-((benzyloxy)carbonyl)-L-phenylalaninol 
• 58917-85-4 N-(benzyloxycarbonyl)-D-phenylalaninol 
• 1452-94-4 ethyl 2-chloronicotinate 
• 59830-60-3 benzyl (1S)-(1-formyl-2-phenylethyl)carbamate 
• 63219-70-5 N-(benzyloxycarbonyl)-D-phenylalaninal 
• 1037827-50-1 (S)-N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-2-(3-phenyl-1H-pyrazol-1-yl)nicotinamide 
• 1037828-54-8 2-(3-phenyl-1H-pyrazol-1-yl)nicotinic acid 
• 1037828-53-7 ethyl 2-(3-phenyl-1H-pyrazol-1-yl)nicotinate 
• 2458-26-6 3-phenylpyrazole 

Relevant articles and documents

Discovery of Novel and Highly Selective Inhibitors of Calpain for the Treatment of Alzheimer's Disease: 2-(3-Phenyl-1H-pyrazol-1-yl)-nicotinamides

Calpain overactivation has been implicated in a variety of pathological disorders including ischemia/reperfusion injury, cataract formation, and neurodegenerative diseases such as Alzheimer's disease (AD). Herein we describe our efforts leading to the ide

Carboxamide compounds and their use as calpain inhibitors

The present invention relates to novel carboxamide compounds and their use for the manufacture of a medicament. The carboxamide compounds are inhibitors of calpain (calcium dependant cysteine proteases). The invention therefore also relates to the use of