103786-20-5

Basic information

• Product Name: Benzene, 1-methoxy-4-[(1E)-3-methyl-1-butenyl]-
• CAS NO: 103786-20-5
• Molecular Formula: C12H16O
• Molecular Weight: 176.258
• Mol File: 103786-20-5.mol
• Article Data: 24

Chemical Properties

• CAS DataBase Reference: Benzene, 1-methoxy-4-[(1E)-3-methyl-1-butenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-methoxy-4-[(1E)-3-methyl-1-butenyl]-(103786-20-5)
• EPA Substance Registry System: Benzene, 1-methoxy-4-[(1E)-3-methyl-1-butenyl]-(103786-20-5)

Safety Data

• Hazardous Substances Data: 103786-20-5(Hazardous Substances Data)

Upstream product

• 3179-10-0 (E)-1-methoxy-4-(2-nitrovinyl)benzene 
• 625-81-0 diisopropyl zinc 
• 75-30-9 2-iodo-propane 
• 10288-13-8 1,2-dibromo-3-methylbutane 
• 5720-07-0 4-methoxyphenylboronic acid 
• 1530-38-7 ((4-methoxyphenyl)methyl)triphenylphosphonium bromide 
• 78-84-2 isobutyraldehyde 
• 943-89-5 (E)-3-(4-methoxyphenyl)acrylic acid 
• 637-69-4 4-Methoxystyrene 
• 123-11-5 4-methoxy-benzaldehyde 
• 3179-10-0 1-methoxy-4-(2-nitro-vinyl)-benzene 
• 1539-32-8 4-isopropyl-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester 
• 14425-64-0 4-methoxyphenethyl bromide 
• 131161-70-1 1-(2-cyclopropylethyl)-4-methoxybenzene 

Downstream Products

• 622-67-3 1-methoxy-4-(3-methylbutyl)benzene 
• 4097-51-2 4-isopentyl-2,6-dinitro-phenol 
• 1805-61-4 p-isoamylphenol 

Relevant articles and documents

Visible-light-mediated alkylation of 4-alkyl-1,4-dihydropyridines with alkenyl sulfones

Herein we report a mild, general protocol for visible-light-mediated alkylation of 4-alkyl-1,4-dihydropyridines with alkenyl sulfones. The protocol permits efficient functionalization of sulfones with a broad range of cyclic and acyclic secondary and tert

A Highly Reduced Ni-Li-Olefin Complex for Catalytic Kumada-Corriu Cross-Couplings

The catalytic activity of a highly reduced Ni catalyst in the context of a Kumada-Corriu cross-coupling has been studied. This nickel complex is characterized by its high electron density, stabilized by simple olefin ligands in combination with two Li ions. Landmark reactivity has been found with this precatalyst which operates at cryogenic temperatures, thus allowing the presence of sensitive functionalities. Structural elucidation of oxidative addition intermediates and their reactivity suggest highly reduced species being operative in the C-C bond forming event.

Enantioselective Oxy-Heck–Matsuda Arylations: Expeditious Synthesis of Dihydrobenzofuran Systems and Total Synthesis of the Neolignan (?)-Conocarpan

This work discloses the first examples of an effective enantioselective oxy-Heck–Matsuda reaction using a variety of styrenic olefins to generate chiral dihydrobenzofurans. The reaction proceeds in moderate to good yields, with high trans diastereoselectivity (up to 20:1) in enantioselectivities up to 90:10 using the N,N-ligand pyrimidine-bisoxazoline (PyriBox). The oxy-Heck–Matsuda reactions were carried out under mild conditions and rather low catalyst loadings. The feasibility and practicality of the process is demonstrated by a concise total synthesis of the neolignan (?)-conocarpan. X-ray diffraction of an advanced brominated intermediate in the route to (?)-conocarpan has allowed the unequivocal assignment of the absolute stereochemistry of the oxy-Heck–Matsuda aryldihydrobenzofuran products. A rationale for the mechanism operating in these enantioselective oxy-Heck–Matsuda reactions is also presented. (Figure presented.).