103842-08-6

Basic information

• Product Name: 3,2',6'-tris(N-benzyloxycarbonyl)-3'-deoxy-3''-N-(trifluoroacetyl)kanamycin B
• Synonyms: 3,2',6'-tris(N-benzyloxycarbonyl)-3'-deoxy-3''-N-(trifluoroacetyl)kanamycin B
• CAS NO: 103842-08-6
• Molecular Weight: 965.932
• Mol File: 103842-08-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3,2',6'-tris(N-benzyloxycarbonyl)-3'-deoxy-3''-N-(trifluoroacetyl)kanamycin B(CAS DataBase Reference)
• NIST Chemistry Reference: 3,2',6'-tris(N-benzyloxycarbonyl)-3'-deoxy-3''-N-(trifluoroacetyl)kanamycin B(103842-08-6)
• EPA Substance Registry System: 3,2',6'-tris(N-benzyloxycarbonyl)-3'-deoxy-3''-N-(trifluoroacetyl)kanamycin B(103842-08-6)

Safety Data

• Hazardous Substances Data: 103842-08-6(Hazardous Substances Data)

Upstream product

• 13139-17-8 N-(Benzyloxycarbonyloxy)succinimide 
• 32986-56-4 tobramycin 
• 383-63-1 ethyl trifluoroacetate, 

Downstream Products

• 533923-30-7 C₆₂H₇₀F₃N₇O₂₁ 
• 533923-31-8 C₅₃H₆₇N₇O₁₉ 

Relevant articles and documents

Probing the functional requirements of the L-haba side-chain of amikacin - Synthesis, 16S A-site rRNA binding, and antibacterial activity

The l-amino group in amikacin was acylated with a variety of 2-hydroxy aminocarboxylic acids to probe the effect of acylation on ribosomal binding and antibacterial activity. The N-hydroxy urea analogue of amikacin (8a) in which the 2-S-hydroxyl-bearing carbon was replaced by an N-OH group was equally active against S. aureus and E. coli in vitro. The analogous tobramycin variant 9 was more active than amikacin.