103861-40-1

Basic information

• Product Name: 1-chloro-3-(2,6-dimethyl-phenoxy)-propan-2-ol
• Synonyms: 1-chloro-3-(2,6-dimethyl-phenoxy)-propan-2-ol
• CAS NO: 103861-40-1
• Molecular Weight: 214.692
• Mol File: 103861-40-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-chloro-3-(2,6-dimethyl-phenoxy)-propan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-chloro-3-(2,6-dimethyl-phenoxy)-propan-2-ol(103861-40-1)
• EPA Substance Registry System: 1-chloro-3-(2,6-dimethyl-phenoxy)-propan-2-ol(103861-40-1)

Safety Data

• Hazardous Substances Data: 103861-40-1(Hazardous Substances Data)

Upstream product

• 576-26-1 2.6-dimethylphenol 
• 106-89-8 epichlorohydrin 

Downstream Products

• 77216-35-4 1-(2,6-dimethylphenoxy)-3-[[2-(3-indolyl)-1,1-dimethylethyl]amino]-2-propanol 
• 5296-34-4 2,6-dimethylphenyl glycidyl ether 
• 30492-44-5 1-(2,6-Di-tert-butyl-4-methyl-phenoxy)-3-(2,6-dimethyl-phenoxy)-propan-2-ol 

Relevant articles and documents

Antihypertensive indole derivatives of phenoxypropanolamines with β-adrenergic receptor antagonist and vasodilating activity

A series of 25 aryloxypropanolamines containing the 3-indolyl-tert-butyl[i.e., 1,1-dimethyl-2-(1H-indol-3-yl)ethyl] or substituted 3-indolyl-tert-butyl moiety as the N substituent is reported. These compounds have been tested for antihypertensive activity in spontaneously hypertensive rats (SHR), β-adrenergic receptor antagonist action in conscious normotensive rats, vasodilating activity in ganglion-blocked rats with blood pressure maintained by angiotensin II infusion, and for intrinsic sympathomimetic action (ISA) in reserpinized rats. Some of the compounds exhibit antihypertensive activity in combination with β-adrenergic receptor antagonist and vasodilating action. The structure-activity relationships in these tests are discussed.