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103877-07-2

103877-07-2

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103877-07-2 Usage

Uses

(-)-N-Methylphysostigmine is an acetylcholinesterase inhibitor.

Check Digit Verification of cas no

The CAS Registry Mumber 103877-07-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,3,8,7 and 7 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 103877-07:
(8*1)+(7*0)+(6*3)+(5*8)+(4*7)+(3*7)+(2*0)+(1*7)=122
122 % 10 = 2
So 103877-07-2 is a valid CAS Registry Number.
InChI:InChI=1/C16H23N3O2/c1-16-8-9-18(4)14(16)19(5)13-7-6-11(10-12(13)16)21-15(20)17(2)3/h6-7,10,14H,8-9H2,1-5H3/t14-,16+/m1/s1

103877-07-2 Well-known Company Product Price

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  • Sigma-Aldrich

  • (M100)  (−)-N-Methylphysostigmine  analytical standard, for drug analysis

  • 103877-07-2

  • M100-5MG

  • 1,574.82CNY

  • Detail

103877-07-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name [(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N,N-dimethylcarbamate

1.2 Other means of identification

Product number -
Other names Physostigmine analog 33

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:103877-07-2 SDS

103877-07-2Downstream Products

103877-07-2Relevant articles and documents

REACTIONS OF (-)-PHYSOSTIGMINE AND (-)-N-METHYLPHYSOSTIGMINE IN REFLUXING BUTANOL AND AT HIGH TEMPERATURE: FACILE PREPARATION OF (-)-ESEROLINE

Yu, Qian-Sheng,Schoenenberger, Bernhard,Brossi, Arnold

, p. 1271 - 1275 (2007/10/02)

(-)-Physostigmine (1), when refluxed in 1-butanol in the presence of sodium butylate afforded (-)-eseroline (3) in high yield, isolated as fumarate salt.Butyl N-methylcarbamate (4) was obtained from the mother liquor. (-)-N-Methylphysostigmine (2), prepared from 3 and dimethylcarbamoyl chloride, underwent under these conditions, similar decomposition suggesting that formation of 3 from 1 and 2 is the result of a nucleophilic substitution.Subliming, or distilling 1, in high vacuum afforded (-)-eseroline (3) and methyl isocyanate trapped by 1-butanol as butyl N-methylcarbamate (4).Compound 2 distilled without decomposition.It is suggested that pyrolysis of 1, therefore, proceeds by fragmentation, forming N-methylisocyanate and (-)-eseroline (3) as reaction products.

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