103929-62-0

Basic information

• Product Name: 5-hydroxy-1,3-dimethyl-5-phenylpyrimidine-2,4,6(1H,3H,5H)-trione
• Synonyms: 5-hydroxy-1,3-dimethyl-5-phenylpyrimidine-2,4,6(1H,3H,5H)-trione
• CAS NO: 103929-62-0
• Molecular Weight: 248.238
• Mol File: 103929-62-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-hydroxy-1,3-dimethyl-5-phenylpyrimidine-2,4,6(1H,3H,5H)-trione(CAS DataBase Reference)
• NIST Chemistry Reference: 5-hydroxy-1,3-dimethyl-5-phenylpyrimidine-2,4,6(1H,3H,5H)-trione(103929-62-0)
• EPA Substance Registry System: 5-hydroxy-1,3-dimethyl-5-phenylpyrimidine-2,4,6(1H,3H,5H)-trione(103929-62-0)

Safety Data

• Hazardous Substances Data: 103929-62-0(Hazardous Substances Data)

Upstream product

• 7391-66-4 1,3-dimethyl-5-phenyl-pyrimidine-2,4,6(1H,3H,5H)-trione 
• 83-13-6 diethyl 2-phenylmalonate 
• 591-50-4 iodobenzene 
• 2613-89-0 phenylmalonic acid 

Downstream Products

• 5841-66-7 3-Methyl-5-phenyl-oxazol-2,4(3H,5H)-dion 

Relevant articles and documents

Method for greenly synthesizing 5-hydroxy-5-alkyl disubstituted barbituric acid derivative by amine catalysis of air oxidation

The invention relates to the field of oxidative synthesis, and in particular, relates to a 5-hydroxy-5-alkyl disubstituted barbituric acid derivative greenly synthesized by amine catalysis of air oxidation and a method thereof. The amine-catalyzed oxidation reaction of a 5-substituted 1,3-dimethylbarbituric acid derivative is studied; reaction catalysts and solvents are screened, hydroxylation ofalpha-C-H of 5-aryl or benzyl substituted barbituric acid compounds is found out to be realized through catalytic reaction under different conditions. The method has the following characteristics: (1)air is used as the source of hydroxyl functional groups, so the requirements of green development are met; (2) easily available and cheap alkali R3N rather than expensive metal catalysts is used; and(3) stoichiometric harmful phosphine compounds are prevented from being used as additives and reductants.