103956-99-6Relevant articles and documents
10'-Apolycopin-10'-ol und 10'-Apolycopin-10'-saeure aus Blueten der Rosenhybride "Marechal Niel"
Maerki-Fischer, Edith,Uebelhart, Peter,Eugster, Conrad Hans
, p. 1994 - 2002 (1987)
The novel 10'-apolycopen-10'-ol (1) and 10'-oic acid (4) were isolated from the yellow petals of the once world-renowned rose hybrid "Marechal Niel".The relative amount of either 1 or 4 produced by the plant depends upon the climatic conditions.Both 1 and
Identification and quantification of apo-lycopenals in fruits, vegetables, and human plasma
Kopec, Rachel E.,Riedl, Ken M.,Harrison, Earl H.,Curley Jr, Robert W.,Hruszkewycz, Damian P.,Clinton, Steven K.,Schwartz, Steven J.
experimental part, p. 3290 - 3296 (2011/07/29)
Research has suggested that lycopene may be metabolized by eccentric cleavage, catalyzed by β-carotene oxygenase 2, resulting in the generation of apo-lycopenals. Apo-6′-lycopenal and apo8′-lycopenal have been reported previously in raw tomato. We now show that several other apolycopenals are also present in raw and processed foods, as well as in human plasma. Apo-lycopenal standards were prepared by in vitro oxidation of lycopene, and a high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method using atmospheric pressure chemical ionization in negative mode was developed to separate and detect the apo-6′-, apo-8′-, apo-10′-, apo-12′-, apo-14′-, and apo-15′-lycopenal products formed in the reaction. Hexane/acetone extracts of raw tomato, red grapefruit, watermelon, and processed tomato products were analyzed, as well as plasma of individuals who had consumed tomato juice for 8 weeks. Apo-6′-, apo-8′-, apo-10′-, apo-12′-, and apo-14′-lycopenals were detected and quantified in all food products tested, as well as plasma. The sum of apo-lycopenals was 6.5 μg/100 g Roma tomato, 73.4μg/100 g tomato paste, and 1.9 nmol/L plasma. We conclude that several apo-lycopenals, in addition to apo-6′- and -8′-lycopenal, are present in lycopene-containing foods. In addition, the presence of apo-lycopenals in plasma may derive from the absorption of apo-lycopenals directly from food and/or human metabolism.
Synthesen von Carotinen mit ψ-Endgruppen und (Z)-Konfiguration an terminalen konjugierten Doppelbindungen
Zumbrunn, Albrecht,Uebelhart, Peter,Eugster, Conrad Hans
, p. 1519 - 1539 (2007/10/02)
Five carotenes bearing (5Z)-ψ-end groups were synthesized and carefully characterized: (5Z)-lycopene (6), (5Z,5'Z)-lycopene (7), (5'Z)-neurosporene (8), (5'Z)-β,ψ-carotene (12), and (5'Z)-εψ-carotene (14).