10402-53-6 Usage
Description
Eprazinone dihydrochloride, a hydrochloride derived from the combination of eprazinone with two molar equivalents of hydrochloric acid, is a pharmaceutical compound with significant therapeutic potential. It is characterized by its ability to enhance pulmonary function, making it a valuable asset in the treatment of respiratory conditions.
Uses
Used in Pharmaceutical Industry:
Eprazinone dihydrochloride is used as a therapeutic agent for improving pulmonary function in patients with chronic bronchitis. Its application is based on its ability to alleviate symptoms and enhance the overall respiratory health of individuals suffering from this condition. By targeting the underlying issues associated with chronic bronchitis, eprazinone dihydrochloride serves as a crucial component in the management and treatment of this prevalent respiratory ailment.
Originator
Mucitux,Riom,France,1969
Manufacturing Process
61.4 g of 0.2M of 1-(2-phenyl-2-ethoxy)piperazine dihydrochloride, 33.5 g
(0.25M) propiophenone, 75 g (0.25M) trioxymethylene, 120 ml of ethanol and
0.4 ml of concentrated HCl are heated under reflux for 4 to 5 hours. The
product is allowed to crystallize, then filtered and washed with alcohol. It is
dried and recrystallized from methanol containing 10% H2O.There is thus obtained 60 g of a white crystalline powder soluble in water.
Yield: 66%. Melting point: 160°C.
Therapeutic Function
Antitussive
Check Digit Verification of cas no
The CAS Registry Mumber 10402-53-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,4,0 and 2 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 10402-53:
(7*1)+(6*0)+(5*4)+(4*0)+(3*2)+(2*5)+(1*3)=46
46 % 10 = 6
So 10402-53-6 is a valid CAS Registry Number.
InChI:InChI=1/C24H32N2O2.2ClH/c1-3-28-23(21-10-6-4-7-11-21)19-26-16-14-25(15-17-26)18-20(2)24(27)22-12-8-5-9-13-22;;/h4-13,20,23H,3,14-19H2,1-2H3;2*1H
