1040264-49-0

Basic information

• Product Name: ethyl 2-amino-4-methoxy-5-(3-morpholin-4-ylpropoxy)benzoate
• Synonyms: ethyl 2-amino-4-methoxy-5-(3-morpholin-4-ylpropoxy)benzoate
• CAS NO: 1040264-49-0
• Molecular Weight: 338.404
• Mol File: 1040264-49-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ethyl 2-amino-4-methoxy-5-(3-morpholin-4-ylpropoxy)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-amino-4-methoxy-5-(3-morpholin-4-ylpropoxy)benzoate(1040264-49-0)
• EPA Substance Registry System: ethyl 2-amino-4-methoxy-5-(3-morpholin-4-ylpropoxy)benzoate(1040264-49-0)

Safety Data

• Hazardous Substances Data: 1040264-49-0(Hazardous Substances Data)

Upstream product

• 1040264-48-9 ethyl 4-methoxy-5-(3-morpholin-4-ylpropoxy)-2-nitrobenzoate 

Downstream Products

• 199327-61-2 7-methoxy-6-(3-morpholinopropoxy)-3,4-dihydroquinazolin-4-one 

Relevant articles and documents

A novel synthesis of EGFR-tyrosine-kinase inhibitors with 4-(indol-3-yl)quinazoline structure

(Chemical Equation Presented) The epidermal growth factor (EGF) family of membrane receptors has been identified as a key element in the complex signaling network that is utilized by various classes of cell-surface receptors. A new synthetic pathway of 4-(indol-3-yl)quinazolines 15 and 16 is described using cross coupling reactions with quinazoline- and indole moieties. The synthesized compound 15 is a new dual and high potent EGFR- and HER-2-tyrosine kinase inhibitor with excellent cytotoxic properties at different cell lines. Furthermore this substance class shows remarkably strong fluorescence.