1040402-85-4Relevant articles and documents
Three-component coupling using arynes and aminosilanes for ortho-selective double functionalization of aromatic skeletons
Morishita, Takami,Fukushima, Hiroyuki,Yoshida, Hiroto,Ohshita, Joji,Kunai, Atsutaka
, p. 5452 - 5457 (2008/12/20)
(Chemical Equation Presented) Arynes were found to couple with aminosilanes and carbonyl compounds in the presence of benzoic acid to provide 2-aminobenzhydrols. Sulfonylimines could also be applied to the reaction, enabling amino and aminomethyl moieties to be incorporated into contiguous positions of aromatic skeletons. Only a small amount of the three-component coupling product was obtained in the absence of benzoic acid, which confirms its vital role in the present reaction.