104199-72-6Relevant articles and documents
The synthesis and inhibitory activity of dethiotrypanothione and analogues against trypanothione reductase
Czechowicz, Josephine A.,Wilhelm, April K.,Spalding, Maroya D.,Larson, Anna M.,Engel, Linnea K.,Alberg, David G.
, p. 3689 - 3693 (2008/02/04)
(Chemical Equation Presented) Trypanothione reductase (TR) catalyzes the NADPH-dependent reduction of trypanothione disulfide (1). TR plays a central role in the trypanosomatid parasite's defense against oxidative stress and has emerged as a promising tar