1042129-33-8

Basic information

• Product Name: methyl 4-(2-chloropyrimidin-4-ylthio)benzoate
• Synonyms: methyl 4-(2-chloropyrimidin-4-ylthio)benzoate
• CAS NO: 1042129-33-8
• Molecular Weight: 280.735
• Mol File: 1042129-33-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 4-(2-chloropyrimidin-4-ylthio)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-(2-chloropyrimidin-4-ylthio)benzoate(1042129-33-8)
• EPA Substance Registry System: methyl 4-(2-chloropyrimidin-4-ylthio)benzoate(1042129-33-8)

Safety Data

• Hazardous Substances Data: 1042129-33-8(Hazardous Substances Data)

Upstream product

• 3934-20-1 2,6-Dichloropyrimidine 
• 6302-65-4 methyl 4-mercaptobenzoate 

Downstream Products

• 1042123-48-7 methyl 4-(2-(4-morpholinophenylamino)pyrimidin-4-ylthio)benzoate 

Relevant articles and documents

THIOPYRIMIDINE-BASED COMPOUNDS AND USES THEREOF

The present invention relates to thiopyrimidine-based compounds that are inhibitors of protein kinases including JAK kinases. In particular, the compounds are selective for JAK1, JAK2 or JAK3 kinases and combinations thereof such as JAK1 and JAK2. The kinase inhibitors can be used in the treatment of kinase associated diseases such as immunological and inflammatory diseases including organ transplants; hyperproliferative diseases including cancer and myeloproliferative diseases; viral diseases; metabolic diseases and vascular diseases.