104330-37-2

Basic information

• Product Name: Benzoic acid, 4-methoxy-, 3-phenylpropyl ester
• CAS NO: 104330-37-2
• Molecular Formula: C17H18O3
• Molecular Weight: 270.328
• Mol File: 104330-37-2.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 4-methoxy-, 3-phenylpropyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-methoxy-, 3-phenylpropyl ester(104330-37-2)
• EPA Substance Registry System: Benzoic acid, 4-methoxy-, 3-phenylpropyl ester(104330-37-2)

Safety Data

• Hazardous Substances Data: 104330-37-2(Hazardous Substances Data)

Upstream product

• 122-97-4 3-Phenyl-1-propanol 
• 100-09-4 4-methoxybenzoic acid 
• 696-62-8 para-iodoanisole 
• 104-88-1 4-chlorobenzaldehyde 
• 300-57-2 allylbenzene 
• 3400-22-4 4-methoxy-N-methylbenzamide 
• 536-45-8 sodium anisate 
• 824-94-2 p-methoxybenzyl chloride 
• 794-94-5 p-Methoxybenzoic anhydride 
• 501-52-0 3-Phenylpropionic acid 
• 299203-18-2 1-triphenylmethoxy-3-phenylpropane 
• 100-07-2 4-methoxy-benzoyl chloride 
• 14629-60-8 trimethyl(3-phenylpropoxy)silane 
• 104330-36-1 p-methoxybenzyl 3-phenylpropyl ether 

Relevant articles and documents

Efficient method for the esterification of carboxylic acids with alcohols using di-2-thienyl carbonate promoted by DMAP and iodine

Reaction of carboxylic acids with alcohols by using an equimolar amount of di-2-thienyl carbonate (2-DTC) in the presence of a catalytic amount of 4-(dimethylamino)pyridine (DMAP) followed by addition of an equimolar amount of iodine proceeded smoothly to afford the corresponding esters and 2(5H)-thiophenone in good to high yields.

Rhodium-catalyzed synthesis of esters from aryl iodides and alcohols: use of alcohols with/without the assistance of aldehydes as carbon monoxide and nucleophile sources

A CO-gas-free rhodium-catalyzed alkoxycarbonylation of aryl iodide with alcohols has been developed. Alcohols, with/without the aid of an aldehyde, were used as a carbon monoxide and nucleophile source. The former synthesis afforded better yields of the alkoxycarbonylated products. Moreover, phenols also afforded phenoxycarbonylation products with high yields.

Advances and mechanistic insight on the catalytic Mitsunobu reaction using recyclable azo reagents

Ethyl 2-arylhydrazinecarboxylates can work as organocatalysts for Mitsunobu reactions because they provide ethyl 2-arylazocarboxylates through aerobic oxidation with a catalytic amount of iron phthalocyanine. First, ethyl 2-(3,4-dichlorophenyl)hydrazinecarboxylate has been identified as a potent catalyst, and the reactivity of the catalytic Mitsunobu reaction was improved through strict optimization of the reaction conditions. Investigation of the catalytic properties of ethyl 2-arylhydrazinecarboxylates and the corresponding azo forms led us to the discovery of a new catalyst, ethyl 2-(4-cyanophenyl)hydrazinecarboxylates, which expanded the scope of substrates. The mechanistic study of the Mitsunobu reaction with these new reagents strongly suggested the formation of betaine intermediates as in typical Mitsunobu reactions. The use of atmospheric oxygen as a sacrificial oxidative agent along with the iron catalyst is convenient and safe from the viewpoint of green chemistry. In addition, thermal analysis of the developed Mitsunobu reagents supports sufficient thermal stability compared with typical azo reagents such as diethyl azodicarboxylate (DEAD). The catalytic system realizes a substantial improvement of the Mitsunobu reaction and will be applicable to practical synthesis.