10438-96-7 Usage
Description
METHYLSULFAMOYL CHLORIDE, a chemical compound, is utilized in the synthesis of various organic compounds and pharmaceuticals. It is known for its reactivity and ability to form derivatives with potential applications in different industries.
Uses
Used in Pharmaceutical Industry:
METHYLSULFAMOYL CHLORIDE is used as a synthetic intermediate for the development of substituted MEK inhibitors. These inhibitors play a crucial role in targeting specific enzymes involved in cellular signaling pathways, which can be beneficial for the treatment of various diseases, including cancer.
Additionally, METHYLSULFAMOYL CHLORIDE is used as a reagent in the preparation of therapeutic compounds. Its ability to form derivatives with potential medicinal properties makes it a valuable asset in the development of new drugs and treatments for a wide range of health conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 10438-96-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,4,3 and 8 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 10438-96:
(7*1)+(6*0)+(5*4)+(4*3)+(3*8)+(2*9)+(1*6)=87
87 % 10 = 7
So 10438-96-7 is a valid CAS Registry Number.
InChI:InChI=1/CH4ClNO2S/c1-3-6(2,4)5/h3H,1H3
10438-96-7Relevant articles and documents
Regioselective C(sp3)-H alkylation of a fructopyranose derivative by 1,6-HAT
Li, Yanru,Miyamoto, Shoto,Torigoe, Takeru,Kuninobu, Yoichiro
, p. 3124 - 3127 (2021)
Regioselective C(sp3)-H alkylation of a fructopyranose derivative using electron-deficient alkenes as alkylation reagents was achieved. The reaction proceededvia1,6-hydrogen atom transfer under photoredox iridium catalysis. Several functional g
Catalytic Sulfamoylation of Alcohols with Activated Aryl Sulfamates
Rapp, Peter B.,Murai, Koichi,Ichiishi, Naoko,Leahy, David K.,Miller, Scott J.
supporting information, p. 168 - 174 (2019/12/30)
We report a new catalytic method for alcohol sulfamoylation that deploys electron-deficient aryl sulfamates as activated group transfer reagents. The reaction utilizes the simple organic base N-methylimidazole, proceeds under mild conditions, and provides
BROMODOMAIN-INHIBITING COMPOUNDS AND PHARMACEUTICAL COMPOSITION COMPRISING SAME FOR PREVENTING OR TREATING A CANCER
-
Page/Page column 45, (2015/11/27)
Provided is a novel compound having bromodomain and extra terminal domain (BET) protein inhibiting activities, and a pharmaceutical composition comprising the same which can be useful for prevention or treatment of precancerous transformation or cancer.