1043906-52-0Relevant articles and documents
Sonogashira coupling catalyzed by the Cu(Xantphos)I–Pd(OAc)2system
Liu, Meilin,Ye, Mingyan,Xue, Yeye,Yin, Guodong,Wang, Dunjia,Huang, Jinkun
, p. 3137 - 3139 (2016)
An efficient Pd(OAc)2/Cu(Xantphos)I system for Sonogashira coupling is disclosed. Aryl bromides/iodides and electron-poor aryl chlorides were suitable for this reaction. The experimental results suggest that Cu(Xantphos)I plays a unique role in which the phosphine ligand coordinates with copper.
Efficient synthesis of monosubstituted 3-alkynylfurans via Suzuki coupling
Yang, Xiaobao,Zhu, Li,Zhou, Yuedong,Li, Zhong,Zhai, Hongbin
, p. 1729 - 1732 (2008/12/22)
A convenient synthesis of monosubstituted 3-alkynyl-furans by Suzuki coupling reaction of 3-furanylboronic acid with substituted acetylene bromides is described. The internal alkyne products were attainable in 50-89% yields from substrates free of relatively acidic protons. Our protocol is expected to find applications in the synthesis of structurally related natural products.
