1044548-92-6

Basic information

• Product Name: 3?amino?1?(3?nitrophenyl)?5,10?dihydro?5,10?dioxo?1H?pyrazolo[1,2?b]phthalazine?2?carbonitrile
• Synonyms: 3?amino?1?(3?nitrophenyl)?5,10?dihydro?5,10?dioxo?1H?pyrazolo[1,2?b]phthalazine?2?carbonitrile
• CAS NO: 1044548-92-6
• Molecular Weight: 361.316
• Mol File: 1044548-92-6.mol
• Article Data: 36

Chemical Properties

• CAS DataBase Reference: 3?amino?1?(3?nitrophenyl)?5,10?dihydro?5,10?dioxo?1H?pyrazolo[1,2?b]phthalazine?2?carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3?amino?1?(3?nitrophenyl)?5,10?dihydro?5,10?dioxo?1H?pyrazolo[1,2?b]phthalazine?2?carbonitrile(1044548-92-6)
• EPA Substance Registry System: 3?amino?1?(3?nitrophenyl)?5,10?dihydro?5,10?dioxo?1H?pyrazolo[1,2?b]phthalazine?2?carbonitrile(1044548-92-6)

Safety Data

• Hazardous Substances Data: 1044548-92-6(Hazardous Substances Data)

Upstream product

• 88-96-0 phthalamide 
• 99-61-6 3-nitro-benzaldehyde 
• 109-77-3 malononitrile 
• 85-44-9 phthalic anhydride 
• 136918-14-4 phthalimide 
• 1445-69-8 2,3-dihydrophthalazine-1,4-dione 

Relevant articles and documents

Copper(II) acetate monohydrate: an efficient and eco-friendly catalyst for the one-pot multi-component synthesis of biologically active spiropyrans and 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives under solvent-free conditions

Abstract: We have studied the catalytic ability of copper(II) acetate monohydrate as a mild, environmentally benign, natural and economical catalyst for the multi-component efficient synthesis of biologically active spiro-4H-pyran derivatives and 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives with excellent yields and short reaction times. The most important advantages of this procedure are its mild, non-toxic and inexpensive catalyst, one-pot synthesis, environmentally benign nature, solvent-free conditions, simple operational procedures, and highly efficient conditions. Graphical Abstract: [Figure not available: see fulltext.]

Mono- and bis-pyrazolophthalazines: Design, synthesis, cytotoxic activity, DNA/HSA binding and molecular docking studies

In an attempt to find new potent cytotoxic compounds, several mono- and bis-pyrazolophthalazines 4a-m and 6a-h were synthesized through an efficient, one-pot, three- and pseudo five-component synthetic approach. All derivatives were evaluated for their in

Catalyst-free, visible light irradiation promoted synthesis of spiroacenaphthylenes and 1H-pyrazolo[1,2-b]phthalazine-5,10-diones in aqueous ethyl lactate

Catalyst-free three-component tandem approach can synthesize spiroacenaphthylenes and 1H-pyrazolo[1,2-b]phthalazine-5,10-diones by Knoevenagel-Michael cyclocondensation via visible light irradiation in aqueous ethyl lactate at room temperature. The signif