1044583-46-1Relevant articles and documents
Dihydro-pyrano[2,3-b]pyridines and tetrahydro-1,8-naphthyridines as CB1 receptor inverse agonists: Synthesis, SAR and biological evaluation
Madsen-Duggan, Christina B.,Debenham, John S.,Walsh, Thomas F.,Yan, Lin,Huo, Pei,Wang, Junying,Tong, Xinchun,Lao, Julie,Fong, Tung M.,Xiao, Jing Chen,Huang, Cathy R.-R.C.,Shen, Chun-Pyn,Stribling, D.Sloan,Shearman, Lauren P.,Strack, Alison M.,Goulet, Mark T.,Hale, Jeffrey J.
scheme or table, p. 3750 - 3754 (2010/09/03)
Synthesis and structure-activity relationships of cannabinoid-1 receptor (CB1R) inverse agonists based on dihydro-pyrano[2,3-b] pyridine and tetrahydro-1,8-naphtyridine scaffolds are presented. Rat food intake and pharmacokinetic evaluation of 13g, 13i, 1