104499-34-5Relevant articles and documents
Investigation of New Chiral 1,3-Oxazolidine-2-thiones: Analytical Separation and Optical Resolution of Racemic Carboxylic Acids and Amino Acids
Nagao, Yoshimitsu,Kumagai, Toshio,Yamada, Shozo,Fujita, Eiichi,Inoue, Yoshinori,et al.
, p. 2361 - 2368 (2007/10/02)
New chiral five-memebered heterocycles, (4S)-(4) and (4R)-4-ethyl-1,3-oxazolidine-2-thione (5), (4S)-4-isopropyl-1,3-oxazolidine-2-thione (6), and (4R,5S)-4-methyl-5-phenyl-1,3-oxazolidine-2-thione (7) have been developed.Among these heterocycles, (4R,5S)-MPOT (7) proved to be an excellent chiral reagent for analytical and efficient separation of racemic products from transformations of chiral carboxylic acids and amino acids.