104605-98-3 Usage
Description
(S)-2-((4-FLUOROPHENOXY)METHYL)OXIRANE, also known as (S)-4-fluorophenylglycidyl ether, is a chemical compound characterized by its molecular formula C10H10FO2. It is a type of epoxide, which is a cyclic ether with a three-membered ring. This colorless liquid exhibits a slightly sweet odor and is soluble in organic solvents. Recognized for its utility in organic synthesis and pharmaceutical production, (S)-2-((4-FLUOROPHENOXY)METHYL)OXIRANE also holds promise as a chiral building block in the synthesis of biologically active compounds. However, it is essential to handle this compound with caution due to its classification as a hazardous substance, which can lead to skin and eye irritation and respiratory issues upon inhalation.
Uses
Used in Organic Synthesis:
(S)-2-((4-FLUOROPHENOXY)METHYL)OXIRANE is used as a reagent in organic synthesis for its ability to facilitate various chemical reactions and form a range of products.
Used in Pharmaceutical Production:
In the pharmaceutical industry, (S)-2-((4-FLUOROPHENOXY)METHYL)OXIRANE is utilized as an intermediate, playing a crucial role in the development and manufacturing of various medications.
Used in Agrochemicals:
(S)-2-((4-FLUOROPHENOXY)METHYL)OXIRANE is also employed in the production of agrochemicals, contributing to the development of substances that aid in the management and protection of crops.
Used as a Chiral Building Block:
In the synthesis of biologically active compounds, (S)-2-((4-FLUOROPHENOXY)METHYL)OXIRANE serves as a valuable chiral building block, enabling the creation of enantiomerically pure compounds with potential applications in various fields, including medicine and biotechnology.
Check Digit Verification of cas no
The CAS Registry Mumber 104605-98-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,4,6,0 and 5 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 104605-98:
(8*1)+(7*0)+(6*4)+(5*6)+(4*0)+(3*5)+(2*9)+(1*8)=103
103 % 10 = 3
So 104605-98-3 is a valid CAS Registry Number.
104605-98-3Relevant articles and documents
Chemoselective Epoxidation of Allyloxybenzene by Hydrogen Peroxide Over MFI-Type Titanosilicate
Fujitani, Tadahiro,Hong, Dachao,Ito, Satoru,Ji, Xinyi,Kon, Yoshihiro,Nakashima, Takuya,Osuga, Ryota,Sato, Kazuhiko,Yokoi, Toshiyuki
, (2020/04/15)
The chemoselective synthesis of 2-(phenoxymethyl)oxirane from allyloxybenzene is achieved with over 90 % yield in a sustainable reaction system using titanium-substituted silicalite-1 (TS-1) as a catalyst, hydrogen peroxide (H2O2) as an oxidant, and a mixture of MeOH/MeCN as a solvent at 40 °C. No acid-catalyzed side reactions prompted by the Lewis acidity of the Ti active site in TS-1 are observed. The TS-1 catalyst can also promote the formation of oxiranes from various p-substituted allyloxybenzenes in good yields. The reaction mechanism is investigated through the reaction with other allyloxy compounds. The results, which are supported by DFT calculations, indicate that an active species of Ti peroxides formed from the reaction of TS-1 with H2O2 selectively oxidizes the allyloxybenzene to 2-(phenoxymethyl)oxirane.
Solvent-Directed Epoxide Opening with Primary Amines for the Synthesis of β-Amino Alcohols
Lizza, Joseph R.,Moura-Letts, Gustavo
supporting information, p. 1231 - 1242 (2017/03/11)
An efficient synthesis of β-amino alcohols from a variety of epoxides and primary unbranched amines in the absence of any catalyst in high yields and regioselectivities is reported. A variety of polar mixed solvent systems allow for the selective formation of secondary amino alcohols over tertiary amino alcohols. The reaction scope extends to a wide variety of aromatic and aliphatic substituted epoxides and primary amines bearing complex functionality.
ANTI-INFECTIVE COMPOUNDS
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Page/Page column 48; 49, (2015/02/25)
The present invention relates to small molecule compounds and their use in the treatment of bacterial infections, in particular Tuberculosis.
