1046781-95-6Relevant articles and documents
A facile preparation of trans-1,2-cyclopropanes containing p-trifluoromethylphenyl group and its application to the construction of pyrazole and cyclopropane ring fused pyridazinone derivatives
Cao, Weiguo,Zhang, Hui,Chen, Jie,Deng, Hongmei,Shao, Min,Lei, Lu,Qian, Jiaxian,Zhu, Yuan
, p. 6670 - 6674 (2008)
A facile methodology for the preparation of highly functionalized trans-1,2-cyclopropanes containing p-trifluoromethylphenyl group 3 is described. Arsonium bromides 1 reacted with electron-deficient olefins 2 in the presence of K2CO3 to provide 3 stereoselectively in moderate to good yields. This process has been successfully applied to the construction of cyclopropane ring fused pyridazinone derivatives 4 or pyrazole derivatives 5.