104693-00-7

Basic information

• Product Name: 1,2-Benzenediol, 4-(2-chloroethyl)-
• CAS NO: 104693-00-7
• Molecular Formula: C8H9ClO2
• Molecular Weight: 172.611
• Mol File: 104693-00-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1,2-Benzenediol, 4-(2-chloroethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Benzenediol, 4-(2-chloroethyl)-(104693-00-7)
• EPA Substance Registry System: 1,2-Benzenediol, 4-(2-chloroethyl)-(104693-00-7)

Safety Data

• Hazardous Substances Data: 104693-00-7(Hazardous Substances Data)

Upstream product

• 120-80-9 benzene-1,2-diol 
• 10597-60-1 hydroxytyrosol 
• 99-40-1 2-chloro-3',4'-dihydroxyacetophenone 

Downstream Products

• 1415490-07-1 S-2-(3,4-diacetoxyphenyl)ethyl ethanethioate 
• 869113-66-6 S-[2-(3,4-dihydroxyphenyl)ethyl] thioacetate 
• 267219-51-2 1,2-dihydroxy-4-(2-mercaptoethyl)benzene 
• 1415490-08-2 (3,4-dihydroxyphenethyl)disulfide 
• 1415490-05-9 1,2-diacetoxy-4-(2-chloroethyl)benzene 
• 69039-02-7 2-(3,4-dihydroxyphenyl)ethyl acetate 
• 10597-60-1 hydroxytyrosol 
• 104693-02-9 [2-(3,4-dihydroxyphenyl)ethyl]dimethylselenonium iodide 
• 104693-01-8 1-<3,4-bis(benzyloxy)phenyl>-2-(methylseleno)ethane 
• 104692-96-8 1-(3,4-dihydroxyphenyl)-2-(methylseleno)ethane 
• 96826-06-1 2-<3,4-bis(benzyloxy)phenyl>-1-chloroethane 

Relevant articles and documents

A three-step, gram-scale synthesis of hydroxytyrosol, hydroxytyrosol acetate, and 3,4-dihydroxyphenylglycol

Hydroxytyrosol and two other polyphenols of olive tree, hydroxytyrosol acetate and 3,4-dihydroxyphenylglycol, are known for a wide range of beneficial activities in human health and prevention from diseases. The inability to isolate high, pure amounts of these natural compounds and the difficult and laborious procedures for the synthesis of them led us to describe herein an efficient, easy, cheap, and scaling up synthetic procedure, from catechol, via microwave irradiation.

Hydroxytyrosol NO donor derivative, and preparation method and application thereof

The invention discloses a hydroxytyrosol NO donor derivative, and a preparation method and an application thereof. The hydroxytyrosol NO donor derivative is used for preparing hypoglycemic and endothelial protection medicines. As a result of in-vitro and in-vivo pharmacological experiments, the above compound has the following pharmacological activities: (1) active oxygen radical removing activity, (2) NO releasing and vasodilation activity, and (3) glucosidase activity inhibition activity and a certain hypoglycemic effect. As a result of in-vivo pharmacokinetic experiments, the derivative can release NO quickly in body such that NO can reach a relatively high level. The invention also provides the preparation method of the hydroxytyrosol NO donor derivative. A modified derivative can be obtained through 4 steps of organic synthesis. The method has the advantages of easy-to-obtain raw materials, mild reaction conditions, simple reaction process operation, and inexpensive agents. The derivative has significant hypoglycemic and vasodilation effects, and can be used in controlling diabetes and vascular complication thereof. The derivative has a great clinical application value.

Dopamine agonists: Effects of charged and uncharged analogues of dopamine

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