1047975-20-1Relevant articles and documents
Microwave-assisted carbamoylation of amines
Azzena, Ugo,Dettori, Giovanna,Pisano, Luisa,Pittalis, Mario
, p. 3623 - 3634 (2007)
The influence of microwave irradiation on the reaction of various amines with benzyl chloroformate and di-tert-butyl dicarbonate was investigated. Microwave irradiation was successfully applied to the carbamoylation of several nonfunctionalized and functionalized amines, including amino acids and nucleobases, leading to satisfactory to high product conversion within very short reaction times. Copyright Taylor & Francis Group, LLC.
Stereoselective alkylation of chiral 2-methyl-4-protected piperazines
-
Page/Page column 7, (2008/06/13)
In an illustrative embodiment, the present invention describes the synthesis of the following compound and similar compounds, in high stereochemical purity by a novel stereoselective alkylation process: 1