104854-58-2Relevant articles and documents
Development of an SNAr Reaction: A Practical and Scalable Strategy to Sequester and Remove HF
Blacker, A. John,Moran-Malagon, Gabriel,Powell, Lyn,Reynolds, William,Stones, Rebecca,Chapman, Michael R.
, (2018)
A simple and operationally practical method to sequester and remove fluoride generated through the SNAr reaction between amines and aryl fluorides is reported. Calcium propionate acts as an inexpensive and environmentally benign in situ scrubbe
NaBHT Generated in Situ from BHT and NaO tBu: Crystallographic Characterization and Applications in Buchwald-Hartwig Amination
Semeniuchenko, Volodymyr,Ovens, Jeffrey S.,Braje, Wilfried M.,Organ, Michael G.
, p. 3276 - 3290 (2021/10/12)
NaBHT is a valuable medium-strength base useful for many applications, particularly for Buchwald-Hartwig coupling. The structures of solvent-free NaBHT and its solvates with Et2O, THF, tBuOH, and a THF/tBuOH mixture were established using single-crystal X-ray diffraction. While [NaBHT·Et2O]2 adopts a dimeric structure and crystallizes in a monoclinic cell, [NaBHT·THF]3, [NaBHT·tBuOH]3, and [NaBHT·(THF-tBuOH)]3 prefer a trimeric structure and crystallize in cubic cells. Solvent-free [NaBHT]n is different from solvated NaBHT and from other known sodium phenolates. It is an inorganic polymer that crystallizes in an orthorhombic cell, with a NaO core spreading in the [1 0 0] direction. Agostic interactions of the tBu group hydrogens with Na, which were confirmed for all structures, may help explain the reductive properties of NaBHT. Further, interactions of BHT with tBuONa in solution and in the solid state were examined, reveraling that NaBHT does not need to be prepared from pyrophoric NaH or metallic Na every time. Instead, it can be generated efficiently in or ex situ using NaOtBu in solution or with only a stoichiometric amount of solvent to assist in bringing the reactants together. Application of this methodology was demonstrated with the efficient, solvent-free, and Pd-catalyzed C-N coupling with Pd(NHC) catalysts.
Zirconium(IV) metallocavitands as blue-emitting materials
Iden, Hassan,Bi, Wenhua,Morin, Jean-Francois,Fontaine, Frederic-Georges
, p. 2883 - 2891 (2014/04/03)
A series of zirconium-carboxylate metallocavitands with the general formula [(CpZr)3(μ-κ2,O′,O″CR) 3(μ3-O)(μ2-OH)3]Cl (Cp = cyclopentadienyl; R = C5H4N (5), C6/s
