1048976-22-2Relevant articles and documents
Utility of nitriles in synthesis of pyrido[2,3-d]pyrimidines, thiazolo[3,2-a]pyridines, pyrano[2,3-b]benzopyrrole, and pyrido[2,3-d] benzopyrroles
Mahmoud,El-Bordany,Hassan,El-Azm, F. S. M. Abu
, p. 2507 - 2521 (2007)
3-Aryl-2-cyanoacrylonitriles (1a,b) reacted with 6-aminothiouracil, 2-ethoxy carbonylmethyl-4-oxo-Δ2-thiazoline, 2-cyanomethyl-4-oxo-Δ2- thiazoline and indan-2-one to give pyrido[2,3-d]pyrimidines, thiazolo[3,2-a]pyridines, pyrano [2,3-b]benzopyrrole and pyrido[2,3-b] benzopyrrole, respectively. The IR, MS and 1H-NMR of the synthesized compounds were discussed. The antimicrobial activity of some of the synthesized compounds was tested. Copyright Taylor & Francis Group, LLC.