1049032-75-8

Basic information

• Product Name: N-(2-bromo-5-fluorophenyl)-3,4-methylenedioxybenzamide
• Synonyms: N-(2-bromo-5-fluorophenyl)-3,4-methylenedioxybenzamide
• CAS NO: 1049032-75-8
• Molecular Weight: 338.133
• Mol File: 1049032-75-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(2-bromo-5-fluorophenyl)-3,4-methylenedioxybenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-bromo-5-fluorophenyl)-3,4-methylenedioxybenzamide(1049032-75-8)
• EPA Substance Registry System: N-(2-bromo-5-fluorophenyl)-3,4-methylenedioxybenzamide(1049032-75-8)

Safety Data

• Hazardous Substances Data: 1049032-75-8(Hazardous Substances Data)

Upstream product

• 25054-53-9 3,4-(methylenedioxy)benzoyl chloride 
• 1003-99-2 2-bromo-5-fluoroaniline 

Relevant articles and documents

Synthesis and biological properties of benzothiazole, benzoxazole, and chromen-4-one analogues of the potent antitumor agent 2-(3,4-dimethoxyphenyl)-5- fluorobenzothiazole (PMX 610, NSC 721648)

New fluorinated 2-aryl-benzothiazoles, -benzoxazoles, and -chromen-4-ones have been synthesized and their activity against MCF-7 and MDA 468 breast cancer cell lines compared with the potent antitumor benzothiazole 5. Analogues such as 9a,b and 12a,d yielded submicromolar GI50 values in both cell lines; however, none of the new compounds approached 5 in terms of antitumor potency. For 5, binding to the aryl hydrocarbon receptor appeared to be necessary but not sufficient for growth inhibition.