105128-95-8

Basic information

• Product Name: 4-(5-Bromo-2-pyrimidinyloxy)-3-chloroaniline
• Synonyms: 4-(5-Bromo-2-pyrimidinyloxy)-3-chloroaniline
• CAS NO: 105128-95-8
• Molecular Weight: 300.542
• Mol File: 105128-95-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(5-Bromo-2-pyrimidinyloxy)-3-chloroaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(5-Bromo-2-pyrimidinyloxy)-3-chloroaniline(105128-95-8)
• EPA Substance Registry System: 4-(5-Bromo-2-pyrimidinyloxy)-3-chloroaniline(105128-95-8)

Safety Data

• Hazardous Substances Data: 105128-95-8(Hazardous Substances Data)

Upstream product

• 3964-52-1 2-chloro 4-aminophenol 
• 32779-36-5 5-Bromo-2-chloropyrimidine 

Downstream Products

• 120997-75-3 methyl N-<4-(5-bromo-2-pyrimidinyloxy)-3-chlorophenyl>aminothio-N-octylcarbamate 
• 138193-71-2 1-[4-(5-Bromo-pyrimidin-2-yloxy)-3-chloro-phenyl]-3-(2,6-dinitro-benzoyl)-urea 
• 138193-62-1 1-[4-(5-Bromo-pyrimidin-2-yloxy)-3-chloro-phenyl]-3-(2-cyano-benzoyl)-urea 
• 105128-93-6 N-[4-(5-bromo-2-pyrimidinyloxy)-3-chlorophenyl]-N'-(2-nitrobenzoyl)-urea 

Relevant articles and documents

Synthesis and antitumor activities of novel benzoylphenylurea derivatives

Seventy novel benzoylphenylurea compounds were synthesized and their antitumor activities were examined in vivo against P388 leukemia. N-(2-Nitrobenzoyl)-N'-[4-(2-pyrimidinyloxy)phenyl]ureas showed the highest antitumor activities when dosed intraperitoneally or orally. Their structure-activity relationships were examined with particular focus on the position and the variety of substituent on each aryl ring.