105191-64-8 Usage
Description
Ethyl 6-bromo-1-benzothiophene-2-carboxylate is a chemical compound with the molecular formula C12H9BrO2S. It is a derivative of benzothiophene that contains a bromo substitution at the 6-position and an ethyl ester group on the 2-carboxylate. Its unique structure and functional groups make it a valuable intermediate for the preparation of drugs, agrochemicals, and other fine chemicals.
Used in Pharmaceutical Research:
Ethyl 6-bromo-1-benzothiophene-2-carboxylate is used as a building block for the synthesis of various biologically active compounds. Its unique structure and functional groups make it a valuable intermediate for the preparation of drugs.
Used in Organic Synthesis:
Ethyl 6-bromo-1-benzothiophene-2-carboxylate is used as a reagent in cross-coupling reactions and other transformations in organic chemistry.
Used in Agrochemicals:
Ethyl 6-bromo-1-benzothiophene-2-carboxylate is used as a building block for the synthesis of various agrochemicals.
Used in Fine Chemicals:
Ethyl 6-bromo-1-benzothiophene-2-carboxylate is used as a building block for the preparation of other fine chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 105191-64-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,1,9 and 1 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 105191-64:
(8*1)+(7*0)+(6*5)+(5*1)+(4*9)+(3*1)+(2*6)+(1*4)=98
98 % 10 = 8
So 105191-64-8 is a valid CAS Registry Number.
105191-64-8Relevant articles and documents
Amide-Amine Replacement in Indole-2-carboxamides Yields Potent Mycobactericidal Agents with Improved Water Solubility
Tan, Yu Jia,Li, Ming,Gunawan, Gregory Adrian,Nyantakyi, Samuel Agyei,Dick, Thomas,Go, Mei-Lin,Lam, Yulin
supporting information, p. 704 - 712 (2020/11/30)
Indolecarboxamides are potent but poorly soluble mycobactericidal agents. Here we found that modifying the incipient scaffold by amide-amine substitution and replacing the indole ring with benzothiophene or benzoselenophene led to striking (10-20-fold) im
MODULATORS FOR NICOTINIC ACETYLCHOLINE RECEPTOR α2 AND α4 SUBUNITS
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Page/Page column 37; 43; 44, (2016/12/22)
Positive allosteric modulators (PAMs) of nicotinic acetylcholine receptors (nAChR) are important therapeutic candidates as well as valuable research tools. We identified a novel type II PAM, (R)-7-bromo-N-(piperidin-3-yl)benzo[b]thiophene-2-carboxamide (B
Novel 1-Heteroaryl-3-Azabicyclo[3.1.0]Hexanes Methods For Their Preparation And Their Use As Medicaments
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Paragraph 0299-0301, (2014/10/16)
The invention provides novel 1-heteroaryl-3-azabicyclo[3.1.0]hexanes, and related processes and intermediates for preparing these compounds, as well as compositions and methods employing these compounds for the treatment and/or prevention of central nervo