1051971-75-5

Basic information

• Product Name: Di(4-pyridylethinyl) zinc bis[3-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]phenyl]porphyrin-ethinyl dimer
• Synonyms: Di(4-pyridylethinyl) zinc bis[3-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]phenyl]porphyrin-ethinyl dimer;Dipyridyl zinc porphyrin diMer
• CAS NO: 1051971-75-5
• Molecular Formula: C₁₁₀H₁₀₀N₁₀O₁₆Zn₂
• Molecular Weight: 1948.85
• Mol File: 1051971-75-5.mol
• Article Data: 2

Chemical Properties

• Appearance: solid
• CAS DataBase Reference: Di(4-pyridylethinyl) zinc bis[3-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]phenyl]porphyrin-ethinyl dimer(CAS DataBase Reference)
• NIST Chemistry Reference: Di(4-pyridylethinyl) zinc bis[3-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]phenyl]porphyrin-ethinyl dimer(1051971-75-5)
• EPA Substance Registry System: Di(4-pyridylethinyl) zinc bis[3-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]phenyl]porphyrin-ethinyl dimer(1051971-75-5)

Safety Data

• Hazardous Substances Data: 1051971-75-5(Hazardous Substances Data)

Usage

General Description

Di(4-pyridylethinyl) zinc bis[3-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]phenyl]porphyrin-ethinyl dimer is a complex chemical compound containing a zinc atom bound to two pyridyl groups and a porphyrin-ethinyl dimer. The porphyrin-ethinyl dimer consists of a porphyrin ring with two ethinyl groups attached to it. The zinc atom is coordinated with two bis[3-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]phenyl]porphyrin-ethinyl dimers, which are large organic molecules containing multiple phenyl and ethoxy groups. This complex chemical structure suggests potential applications in catalysis, photodynamic therapy, and nanotechnology. The unique combination of metal and organic groups in this chemical compound may offer promising properties for various scientific and industrial uses.

Upstream product

• 2510-22-7 4-pyridylacetylene 
• 1051971-74-4 Zn₂((MeO(CH₂CH₂O)3C₆H₄)2(Br)C₂₀H₈N₂C₄C₂₀H₈N₄(Br)(C₆H₄(OCH₂CH₂)3OMe)2) 
• 15854-87-2 4-iodopyridine 
• 1144514-33-9 Zn₂((MeO(CH₂CH₂O)3C₆H₄)2(HCC)C₂₀H₈N₄C₄C₂₀H₈N₄(C₆H₄(OCH₂CH₂)3OMe)2(CCH)) 
• 1051971-74-4 C₉₆H₉₂Br₂N₈O₁₆Zn₂ 

Relevant articles and documents

Synthesis of hydrophilic conjugated porphyrin dimers for one-photon and two-photon photodynamic therapy at NIR wavelengths

We report the synthesis of a series of hydrophilic butadiyne-linked conjugated zinc porphyrin dimers (1-7), designed as photodynamic therapy (PDT) agents. These porphyrin dimers exhibit exceptionally high two-photon absorption cross sections (δmax≈ 8,000-17,000 GM) and red-shifted linear absorption spectra (λmax≈ 700-800 nm) making them ideal candidates for one-photon and two-photon excited photodynamic therapy. Four polar triethyleneglycol substituents are positioned along the sides of each dimer, but, on their own, these TEG chains do not confer sufficient solubility in aqueous physiological media for reproducible delivery into live cells. Charged cationic (methylpyridinium and trimethylammonium) and anionic (sulfonate and carboxylate) substituents have been appended to the meso-positions of porphyrin dimers using three synthetic strategies: 1) Suzuki coupling, 2) Sonogashira coupling, and 3) nucleophilic Senge arylation. Approaches 1 and 3 both allow attachment of aromatic substituents directly to the meso-positions of porphyrins. Approach 2 provides a route to hydrophilic porphyrin dimers with an ethyne link between the porphyrin and the polar aromatic substituent. The palladium-catalysed approaches 1 and 2 allow the synthesis of a broader range of meso-capped porphyrins, as many aryl halides are available. However the synthesis of the intermediate required for these routes necessitates a statistical reaction step, which decreases the overall yield. On the other hand, Senge-arylation provides highly regioselective nucleophilic aromatic substitution, and offers higher overall yield than the other routes. All these charged dimers exhibit good solubility in polar solvents (e.g. methanol) and aqueous solvent mixtures (aqueous DMSO or DMF).